Asacol and Tiazac drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Asacol (mesalamine) and Tiazac (diltiazem hydrochloride). Common drug interactions include abdominal tenderness among females.
The phase IV clinical study analyzes what interactions people have when they take Asacol and Tiazac. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Asacol?
Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.
What is Tiazac?
Tiazac has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 4,761 Tiazac users. Check the latest studies of Tiazac.
21 people who take Asacol and Tiazac together, and have interactions are studied.

What are the common drug interactions of Asacol and Tiazac, by gender? *:
female:
- Abdominal tenderness
- Diarrhoea
- Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
- Cellulitis (infection under the skin)
- Gallbladder disorder
- Nasopharyngitis (inflammation of the nasopharynx)
- Poor venous access
- Renal failure acute (rapid kidney dysfunction)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Urinary tract infection
male:
n/a
What are the common drug interactions of Asacol and Tiazac, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Haematochezia (passage of stools containing blood)
- Joint swelling
- Nausea (feeling of having an urge to vomit)
- Pyrexia (fever)
50-59:
- Abdominal tenderness
- Drug hypersensitivity
- Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
- Malaise (a feeling of general discomfort or uneasiness)
- Weight decreased
- Abdominal pain lower
- Cellulitis (infection under the skin)
- Diarrhoea
- Gallbladder disorder
- Nasopharyngitis (inflammation of the nasopharynx)
60+:
- Abdominal pain
- Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
- Cough
- Dizziness (excl vertigo)
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
- Fatigue (feeling of tiredness)
- Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
- Myalgia (muscle pain)
- Nausea (feeling of having an urge to vomit)
- Nocturia (the need to get up in the night to urinate)
What are the existing conditions these people have? *
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 17 people, 80.95%
- Urinary Tract Infection: 3 people, 14.29%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.52%
- Cholangitis Sclerosing (infection and obstruction of bile duct): 2 people, 9.52%
* Approximation only. Some reports may have incomplete information.
Do you take Asacol and Tiazac?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Asacol and Tiazac:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Asacol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tiazac:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Asacol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tiazac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on mesalamine and diltiazem hydrochloride (the active ingredients of Asacol and Tiazac, respectively), and Asacol and Tiazac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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