Asacol and Vistaril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Asacol (mesalamine) and Vistaril (hydroxyzine hydrochloride). Common drug interactions include memory impairment among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Asacol and Vistaril. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Asacol?

Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.



On Jul, 13, 2026

17 people who take Asacol and Vistaril together, and have interactions are studied.

Asacol and Vistaril drug interactions.

What are the common drug interactions of Asacol and Vistaril, by gender? *:

female:

  1. Memory impairment
  2. Muscle twitching
  3. Oedema peripheral (superficial swelling)
  4. Pain
  5. Psychotic behaviour
  6. Self injurious behaviour
  7. Visual impairment
  8. Headache (pain in head)
  9. Oropharyngeal pain
  10. Drug ineffective

male:

  1. Abdominal pain upper
  2. Headache (pain in head)
  3. Alanine aminotransferase decreased
  4. Anger
  5. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  6. Asthenia (weakness)
  7. Biliary dilatation
  8. Blood iron decreased
  9. Bone pain
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the common drug interactions of Asacol and Vistaril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Haemorrhage (bleeding)
  2. Nausea (feeling of having an urge to vomit)
  3. Diarrhoea
  4. Pain
  5. Abdominal pain upper
  6. Arthralgia (joint pain)
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  8. Asthenia (weakness)
  9. Gastrointestinal pain

30-39:

n/a

40-49:

  1. Uterine haemorrhage (uterine bleeding)
  2. Vaginal haemorrhage (vaginal bleeding)
  3. Amphetamines positive
  4. Drug ineffective
  5. Headache (pain in head)
  6. Oedema peripheral (superficial swelling)

50-59:

  1. Headache (pain in head)
  2. Bedridden
  3. Influenza like illness
  4. Injection site erythema (redness at injection site)
  5. Injection site warmth
  6. Myalgia (muscle pain)
  7. Oropharyngeal pain
  8. Pyrexia (fever)
  9. Cough
  10. Drug ineffective

60+:

  1. Bone pain
  2. Feeling jittery
  3. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  4. Headache (pain in head)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Pneumonia
  7. Staphylococcal infection (an infection with staphylococcus bacteria)
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Abnormal sleep-related event
  10. Adverse event

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 4 people, 23.53%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 23.53%
  3. Depression: 4 people, 23.53%
  4. Bipolar Disorder (mood disorder): 3 people, 17.65%
  5. Sleep Disorder: 3 people, 17.65%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 17.65%
  7. Panic Disorder: 3 people, 17.65%
  8. Pain: 3 people, 17.65%
  9. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 17.65%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Asacol and Vistaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Asacol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vistaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Asacol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vistaril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mesalamine and hydroxyzine hydrochloride (the active ingredients of Asacol and Vistaril, respectively), and Asacol and Vistaril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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