Astepro and Combivent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Astepro (azelastine hydrochloride) and Combivent (albuterol sulfate; ipratropium bromide). Common drug interactions include oedema among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Astepro and Combivent. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Astepro?

Astepro has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 3,336 Astepro users. Check the latest studies of Astepro.

What is Combivent?

Combivent has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in asthma. eHealthMe is studying from 35,341 Combivent users. Check the latest studies of Combivent.

On Jul, 11, 2026

39 people who take Astepro and Combivent together, and have interactions are studied.

Astepro and Combivent drug interactions.

What are the common drug interactions of Astepro and Combivent, by gender? *:

female:

Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Oral candidiasis (fungal infection of mouth)
Pain
Peripheral swelling
Polyuria (production of too much dilute urine)
Rectal haemorrhage (bleeding from anus)
Rhinorrhoea (watery mucus discharge from the nose)
Spinal pain (pain in spine)
Sputum discoloured

male:

Pain
Hypokalaemia (low potassium)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Arthralgia (joint pain)
Bradycardia (abnormally slow heart action)
Cardiac failure congestive
Chest pain
Decreased appetite
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Astepro and Combivent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal discomfort
Cataract (clouding of the lens inside the eye)
Diarrhoea
Drug ineffective
Fatigue (feeling of tiredness)
Feeling jittery
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hot flush (sudden feelings of heat)
Hypersensitivity

50-59:

Anxiety
Chemical burn of skin
Emotional distress
Erythema (redness of the skin)
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Gout (uric acid crystals building up in the body)
Hypokalaemia (low potassium)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Pain

60+:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Costochondritis (chest wall pain)
Drug ineffective
Fall
Fibromyalgia (a long-term condition which causes pain all over the body)
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Peripheral swelling

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 17.95%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 17.95%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 15.38%
Insomnia (sleeplessness): 4 people, 10.26%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 10.26%
Stress And Anxiety: 4 people, 10.26%
Urinary Tract Infection: 4 people, 10.26%
Pain: 3 people, 7.69%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 7.69%
Cough: 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Astepro and Combivent?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously