Atarax and Glucovance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atarax (hydroxyzine hydrochloride) and Glucovance (glyburide; metformin hydrochloride). Common drug interactions include diarrhoea among females and hyperlactacidaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Atarax and Glucovance. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

What is Glucovance?

Glucovance has active ingredients of glyburide; metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 6,302 Glucovance users. Check the latest studies of Glucovance.

On Jul, 26, 2026

32 people who take Atarax and Glucovance together, and have interactions are studied.

Atarax and Glucovance drug interactions.

What are the common drug interactions of Atarax and Glucovance, by gender? *:

female:

Diarrhoea
Pancreatitis acute (sudden inflammation of pancreas)
Renal injury (kidney injury)
Weight decreased
Affective disorder (mental disorder)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood pressure decreased
Cardiac failure congestive
Cholecystitis acute (rapid infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

male:

Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Pain
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Respiratory depression (respiration has a rate below 12 breaths)
Arrhythmia (irregular heartbeat)
Alanine aminotransferase increased
Anticonvulsant drug level decreased
Aspartate aminotransferase increased
Blood pressure increased

What are the common drug interactions of Atarax and Glucovance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cholecystitis acute (rapid infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Diarrhoea
Discomfort
Ear infection
Emotional distress
Haematoma (collection of blood outside the blood vessels)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pain

30-39:

n/a

40-49:

Pancreatitis (inflammation of pancreas)

50-59:

Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat)
Dyspnoea (difficult or laboured respiration)
Hepatic failure (liver failure)
Fibromyalgia (a long-term condition which causes pain all over the body)
Pain
Arrhythmia (irregular heartbeat)
Affective disorder (mental disorder)

60+:

Pancreatitis chronic (chronic inflammation of pancreas)
Somnolence (a state of near-sleep, a strong desire for sleep)
Blood pressure increased
C-reactive protein increased
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Disturbance in attention
Headache (pain in head)
Heart rate decreased
Heart rate increased
Hypervigilance

What are the existing conditions these people have? *

Type 2 Diabetes: 19 people, 59.38%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 11 people, 34.38%
Depression: 10 people, 31.25%
Hiv Infection: 8 people, 25.00%
Pain: 6 people, 18.75%
Sleep Disorder: 5 people, 15.62%
Insomnia (sleeplessness): 5 people, 15.62%
High Blood Pressure: 5 people, 15.62%
High Blood Cholesterol: 5 people, 15.62%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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