Atarax and Iclusig drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atarax (hydroxyzine hydrochloride) and Iclusig (ponatinib hydrochloride). Common drug interactions include arthralgia among females and hepatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Atarax and Iclusig. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

What is Iclusig?

Iclusig has active ingredients of ponatinib hydrochloride. eHealthMe is studying from 6,109 Iclusig users. Check the latest studies of Iclusig.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

19 people who take Atarax and Iclusig together, and have interactions are studied.

What are the common drug interactions of Atarax and Iclusig, by gender? *:

female:

Arthralgia (joint pain)
Bone marrow failure
Capillary leak syndrome (capillary leaks plasma)
Ear infection staphylococcal (ear infection by staphylococcal bacteria)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Headache (pain in head)
Herpes zoster
Lupus-like syndrome (a disease symptom matches with lupus an immune disease)
Mucosal inflammation (infection of mucous membrane)
Neuropathy peripheral (surface nerve damage)

male:

Hepatitis (inflammation of the liver)
Drug level increased
Acute respiratory distress syndrome
Altered state of consciousness (altered state of mind)
Anaemia (lack of blood)
Bk virus infection
Blood potassium decreased
Cytomegalovirus infection
Depression
Disease recurrence

What are the common drug interactions of Atarax and Iclusig, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Hepatitis (inflammation of the liver)
Neuropathy peripheral (surface nerve damage)
Pancreatitis acute (sudden inflammation of pancreas)
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
Liver injury
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Arthralgia (joint pain)
Bone marrow failure

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Drug level increased
Hepatic failure (liver failure)
Cytomegalovirus infection
Depression
Disease recurrence
Enterococcus test positive
Epstein-barr virus infection
Exfoliative rash (scaly red generalized skin rash)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Fall

What are the existing conditions these people have? *

Urinary Tract Infection: 10 people, 52.63%
Tumor Lysis Syndrome: 10 people, 52.63%
High Blood Pressure: 10 people, 52.63%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 10 people, 52.63%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 10 people, 52.63%
Arrhythmias (irregular heartbeat): 10 people, 52.63%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 10 people, 52.63%
Respiratory Tract Infection: 4 people, 21.05%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 21.05%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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