Atarax and Prempro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atarax (hydroxyzine hydrochloride) and Prempro (estrogens, conjugated; medroxyprogesterone acetate). Common drug interactions include kidney infection among females and myelodysplastic syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Atarax and Prempro. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

What is Prempro?

Prempro has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. It is often used in menopause. eHealthMe is studying from 42,950 Prempro users. Check the latest studies of Prempro.

On Jul, 24, 2026

34 people who take Atarax and Prempro together, and have interactions are studied.

What are the common drug interactions of Atarax and Prempro, by gender? *:

female:

Kidney infection
Pain
Post procedural cellulitis (post procedural bacterial infection of the skin and soft tissues)
Seroma (a tumour like collection of serum in the tissues)
Vaginal cyst
Vaginal haemorrhage (vaginal bleeding)
Fatigue (feeling of tiredness)
Headache (pain in head)
Renal disorder (kidney disease)
Night sweats (sweating in night)

male:

Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)

What are the common drug interactions of Atarax and Prempro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood cholesterol increased
Blood glucose increased
Blood triglycerides increased
Cardiovascular disorder (heart diseases)
Cystitis (inflammation of the wall of the bladder)
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control

50-59:

Kidney infection
Sinusitis (inflammation of sinus)
Abdominal pain
Breast cancer stage ii
Deformity (disfigurement)
Nausea (feeling of having an urge to vomit)
Pain
Post procedural cellulitis (post procedural bacterial infection of the skin and soft tissues)
Seroma (a tumour like collection of serum in the tissues)
Vaginal cyst

60+:

Drug ineffective
Cold sweat
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Skin irritation
Night sweats (sweating in night)
Vulvovaginal pruritus (vulvovaginal severe itching)
Back pain
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac failure congestive

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 9 people, 26.47%
Menopausal Symptoms: 6 people, 17.65%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 11.76%
Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 8.82%
Type 2 Diabetes: 3 people, 8.82%
Atopy (a genetic disposition to develop an allergic reaction): 3 people, 8.82%
Osteoporosis (bones weak and more likely to break): 2 people, 5.88%
Migraine (headache): 2 people, 5.88%
Hypersensitivity: 2 people, 5.88%
Hepatitis C: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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