Atarax and Sovaldi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atarax (hydroxyzine hydrochloride) and Sovaldi (sofosbuvir). Common drug interactions include pulmonary arterial hypertension among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Atarax and Sovaldi. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

What is Sovaldi?

Sovaldi has active ingredients of sofosbuvir. eHealthMe is studying from 12,697 Sovaldi users. Check the latest studies of Sovaldi.

On Jul, 30, 2026

18 people who take Atarax and Sovaldi together, and have interactions are studied.

What are the common drug interactions of Atarax and Sovaldi, by gender? *:

female:

Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Anaemia (lack of blood)
Asthenia (weakness)
Chest pain
Dizziness
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Palpitations (feelings or sensations that your heart is pounding or racing)

male:

Anaemia (lack of blood)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Fatigue (feeling of tiredness)
Gingival swelling (gums swelling)
Headache (pain in head)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Skin disorder (skin disease)

What are the common drug interactions of Atarax and Sovaldi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood creatine phosphokinase increased
Myalgia (muscle pain)
Arthralgia (joint pain)
Hypoaesthesia (reduced sense of touch or sensation)

40-49:

Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

50-59:

Anaemia (lack of blood)
Arthralgia (joint pain)
Burning sensation
Deafness
Ear disorder
Facial paresis (weakness in facial muscle movement)
Fatigue (feeling of tiredness)
Gingival swelling (gums swelling)
Headache (pain in head)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)

60+:

Anaemia (lack of blood)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Palpitations (feelings or sensations that your heart is pounding or racing)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatocellular carcinoma (liver cancer)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Asthenia (weakness)
Chest pain
Dizziness
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Hepatitis C: 12 people, 66.67%
Oedema Peripheral (superficial swelling): 4 people, 22.22%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 11.11%
Sleep Disorder: 1 person, 5.56%
Seasonal Allergy (allergic condition due to certain season): 1 person, 5.56%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 5.56%
Insomnia (sleeplessness): 1 person, 5.56%
Hiv Infection: 1 person, 5.56%
Hepatitis C Virus Test Positive: 1 person, 5.56%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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