Atarax and Versed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atarax (hydroxyzine hydrochloride) and Versed (midazolam hydrochloride). Common drug interactions include platelet count decreased among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Atarax and Versed. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

What is Versed?

Versed has active ingredients of midazolam hydrochloride. It is often used in sedation during medical procedure. eHealthMe is studying from 6,869 Versed users. Check the latest studies of Versed.



On Jul, 15, 2026

52 people who take Atarax and Versed together, and have interactions are studied.

Atarax and Versed drug interactions.

What are the common drug interactions of Atarax and Versed, by gender? *:

female:

  1. Platelet count decreased
  2. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  3. Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
  4. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  5. Diarrhoea haemorrhagic (bloody diarrhoea)
  6. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  7. Haematoma (collection of blood outside the blood vessels)
  8. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  9. Pleural effusion (water on the lungs)
  10. Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses)

male:

  1. Asthenia (weakness)
  2. Cough
  3. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  4. Chest pain
  5. Headache (pain in head)
  6. Pneumonia
  7. Sputum increased
  8. Acidosis (build-up of carbon dioxide in the blood)
  9. Acute respiratory distress syndrome
  10. Anaemia (lack of blood)

What are the common drug interactions of Atarax and Versed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
  2. Diarrhoea
  3. Diarrhoea haemorrhagic (bloody diarrhoea)
  4. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  5. Haematoma (collection of blood outside the blood vessels)
  6. Pleural effusion (water on the lungs)
  7. Pyrexia (fever)
  8. Septic shock (shock due to blood infection)
  9. Tooth abscess (pus formation in tooth)

10-19:

  1. Febrile neutropenia (fever with reduced white blood cells)

20-29:

n/a

30-39:

  1. Asthenia (weakness)
  2. Cough
  3. Diarrhoea
  4. Dyspnoea (difficult or laboured respiration)
  5. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  6. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  7. Pyrexia (fever)
  8. Acidosis (build-up of carbon dioxide in the blood)
  9. Acute respiratory distress syndrome
  10. Anaemia (lack of blood)

40-49:

  1. Chronic kidney disease
  2. Osteonecrosis (death of bone)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Blood creatinine increased
  5. Bone density decreased
  6. Emotional distress
  7. Hip arthroplasty
  8. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  9. Pain
  10. Renal impairment (severely reduced kidney function)

50-59:

  1. Failure to thrive (inadequate weight gain and physical growth in children)
  2. Hypotension (abnormally low blood pressure)
  3. Laryngeal oedema (swelling of larynx)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Oxygen saturation decreased
  6. Pneumonia viral
  7. Renal failure acute (rapid kidney dysfunction)
  8. Respiratory distress (difficulty in breathing)
  9. Salivary hypersecretion (excess saliva secretion)
  10. Torsade de pointes (a abnormal heart rate with abnormal beating pattern)

60+:

  1. Renal failure (kidney dysfunction)
  2. Encephalopathy (functioning of the brain is affected by some agent or condition)
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Glomerular filtration rate decreased
  5. Hyperkalaemia (damage to or disease of the kidney)
  6. Hypovolaemic shock (shock caused by severe blood or fluid loss)
  7. Nausea (feeling of having an urge to vomit)
  8. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  9. Platelet count decreased
  10. Pulmonary oedema (fluid accumulation in the lungs)

What are the existing conditions these people have? *

  1. Pain: 20 people, 38.46%
  2. Sedation: 17 people, 32.69%
  3. Wheezing (a high-pitched whistling sound made while you breath): 16 people, 30.77%
  4. Cough: 16 people, 30.77%
  5. High Blood Pressure: 15 people, 28.85%
  6. Rickets (softening of bones): 15 people, 28.85%
  7. Nausea (feeling of having an urge to vomit): 14 people, 26.92%
  8. Cystic Fibrosis (disease of the secretary glands): 14 people, 26.92%
  9. Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 14 people, 26.92%
  10. Constipation: 11 people, 21.15%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Atarax and Versed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Versed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atarax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Versed and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride and midazolam hydrochloride (the active ingredients of Atarax and Versed, respectively), and Atarax and Versed (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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