Ativan and Rinvoq drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ativan (lorazepam) and Rinvoq (upadacitinib). Common drug interactions include joint swelling among females and cardiac disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Ativan and Rinvoq. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Ativan?

Ativan has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 78,506 Ativan users. Check the latest studies of Ativan.

What is Rinvoq?

Rinvoq has active ingredients of upadacitinib. eHealthMe is studying from 47,375 Rinvoq users. Check the latest studies of Rinvoq.

On Jul, 11, 2026

59 people who take Ativan and Rinvoq together, and have interactions are studied.

What are the common drug interactions of Ativan and Rinvoq, by gender? *:

female:

Joint swelling
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Pruritus (severe itching of the skin)
Rash
Abdominal discomfort
Arthropathy
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Contusion (a type of hematoma of tissue in which capillaries)
Drug ineffective
Hepatic enzyme increased

male:

Cardiac disorder
Discomfort
Cardiac failure congestive
Depression
Oedema peripheral (superficial swelling)
Prostate cancer
Balance disorder
Dementia (madness)
Dizziness
Gait disturbance

What are the common drug interactions of Ativan and Rinvoq, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Bipolar disorder (mood disorder)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Muscle spasms (muscle contraction)

30-39:

n/a

40-49:

Drug ineffective
Weight increased
Alopecia (absence of hair from areas of the body)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Back disorder
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Decreased appetite
Deep vein thrombosis postoperative (blood clot in a major vein that usually develops in the legs and/or pelvis after operation)
Depression
Dizziness

50-59:

Grip strength decreased
Hand deformity
Headache (pain in head)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic enzyme increased
Hip arthroplasty
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypersensitivity
Hypertension (high blood pressure)

60+:

Cardiac disorder
Discomfort
Urinary tract infection
Abdominal pain
Confusional state
Dehydration (dryness resulting from the removal of water)
Dementia (madness)
Diarrhoea
Fatigue (feeling of tiredness)
Frequent bowel movements

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 43 people, 72.88%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 27 people, 45.76%
Ankylosing Spondylitis (type of arthritis affecting the spine): 19 people, 32.20%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 18 people, 30.51%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 17 people, 28.81%
Psoriasis (immune-mediated disease that affects the skin): 15 people, 25.42%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 15.25%
Depression: 5 people, 8.47%
Thyroid Diseases: 4 people, 6.78%
High Blood Cholesterol: 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

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