Atovaquone and Emend drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atovaquone (atovaquone) and Emend (aprepitant). Common drug interactions include pyrexia among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Atovaquone and Emend. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Atovaquone?

Atovaquone has active ingredients of atovaquone. eHealthMe is studying from 5,786 Atovaquone users. Check the latest studies of Atovaquone.

What is Emend?

Emend has active ingredients of aprepitant. It is often used in nausea. eHealthMe is studying from 13,741 Emend users. Check the latest studies of Emend.

On Jul, 29, 2026

22 people who take Atovaquone and Emend together, and have interactions are studied.

What are the common drug interactions of Atovaquone and Emend, by gender? *:

female:

Pyrexia (fever)
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Vulvovaginal mycotic infection (vulvovaginal fungal infection)
Abdominal pain
Cough
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Anaemia (lack of blood)
Death
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)

male:

Febrile neutropenia (fever with reduced white blood cells)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Diarrhoea
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fibrin d dimer increased
Hyperlipidaemia (presence of excess lipids in the blood)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Hypokalaemia (low potassium)
Insomnia (sleeplessness)

What are the common drug interactions of Atovaquone and Emend, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Adenovirus infection
Cytomegalovirus infection
Diarrhoea
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hypotension (abnormally low blood pressure)
Mucosal inflammation (infection of mucous membrane)

20-29:

n/a

30-39:

Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Rash papular (redness with papule)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

40-49:

Alopecia (absence of hair from areas of the body)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Hyperlipidaemia (presence of excess lipids in the blood)
Insomnia (sleeplessness)
T-cell type acute leukaemia (a form of cancer of the white blood cells)

50-59:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Fibrin d dimer increased
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Hypokalaemia (low potassium)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Ventricular extrasystoles (premature cardiac contraction)

60+:

Pyrexia (fever)
Febrile neutropenia (fever with reduced white blood cells)
Malignant neoplasm progression (cancer tumour came back)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Hypercreatininaemia (high levels of creatine in the blood)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Renal impairment (severely reduced kidney function)
Stomatitis (inflammation of mucous membrane of mouth)
Liver injury
Diarrhoea

What are the existing conditions these people have? *

Neoplasm Malignant (cancer tumour): 10 people, 45.45%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 5 people, 22.73%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 18.18%
Lung Cancer Metastatic (lung cancer spreads to other parts): 3 people, 13.64%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 9.09%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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