Atripla and Mesalamine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Atripla (efavirenz; emtricitabine; tenofovir disoproxil fumarate) and Mesalamine (mesalamine). Common drug interactions include pain among males.
The phase IV clinical study analyzes what interactions people have when they take Atripla and Mesalamine. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Atripla?
Atripla has active ingredients of efavirenz; emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 36,036 Atripla users. Check the latest studies of Atripla.
What is Mesalamine?
Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.
16 people who take Atripla and Mesalamine together, and have interactions are studied.

What are the common drug interactions of Atripla and Mesalamine, by gender? *:
female:
n/a
male:
- Pain
- Emotional distress
- Osteoporosis (bones weak and more likely to break)
- Quality of life decreased
- Disturbance in attention
- Eating disorder
- Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Sleep disorder
- Multiple fractures
What are the common drug interactions of Atripla and Mesalamine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Ankle fracture
- Anxiety
- Bone density decreased
- Bone loss
- Chronic kidney disease
- Emotional distress
- Ligament rupture (tear in ligament)
- Lower limb fracture
- Nephrolithiasis (calculi in the kidneys)
40-49:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Fatigue (feeling of tiredness)
- Pain
- Renal disorder (kidney disease)
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Quality of life decreased
- Dysuria (painful or difficult urination)
50-59:
- Pain
- Emotional distress
- Foot fracture
- Grip strength decreased
- Hand fracture
- Muscle atrophy (a decrease in the mass of the muscle)
- Quality of life decreased
- Bipolar disorder (mood disorder)
- Depression
- Hip fracture
60+:
n/a
What are the existing conditions these people have? *
- High Blood Pressure: 6 people, 37.50%
- Bacterial Infection: 6 people, 37.50%
- Inflammation: 4 people, 25.00%
- High Blood Cholesterol: 4 people, 25.00%
- Asthma: 3 people, 18.75%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 18.75%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 18.75%
- Depression: 3 people, 18.75%
- Headache (pain in head): 3 people, 18.75%
- Fungal Infection: 3 people, 18.75%
* Approximation only. Some reports may have incomplete information.
Do you take Atripla and Mesalamine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Atripla (36,036 reports)
- Mesalamine (28,053 reports)
Browse all drug interactions of Atripla and Mesalamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Atripla:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Mesalamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Atripla and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mesalamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on efavirenz; emtricitabine; tenofovir disoproxil fumarate and mesalamine (the active ingredients of Atripla and Mesalamine, respectively), and Atripla and Mesalamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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