Atripla and Nitrostat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atripla (efavirenz; emtricitabine; tenofovir disoproxil fumarate) and Nitrostat (nitroglycerin). Common drug interactions include decreased activity among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Atripla and Nitrostat. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Atripla?

Atripla has active ingredients of efavirenz; emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 36,036 Atripla users. Check the latest studies of Atripla.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

On Aug, 09, 2026

35 people who take Atripla and Nitrostat together, and have interactions are studied.

Atripla and Nitrostat drug interactions.

What are the common drug interactions of Atripla and Nitrostat, by gender? *:

female:

Decreased activity
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)
Renal tubular disorder (disease of kidney tubules)
Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Muscular weakness (muscle weakness)
Pain in extremity
Ankle fracture
Renal failure (kidney dysfunction)
Multiple fractures
Mobility decreased (ability to move is reduced)
Neck pain
Arthralgia (joint pain)

What are the common drug interactions of Atripla and Nitrostat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Back pain
Dysstasia (difficulty in standing)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Muscular weakness (muscle weakness)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Quality of life decreased
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Bone density decreased
Osteopenia (a condition where bone mineral density is lower than normal)
Chronic kidney disease
Depression
Osteoporosis (bones weak and more likely to break)
Ankle fracture

60+:

Malaise (a feeling of general discomfort or uneasiness)
Blood creatinine increased
Renal disorder (kidney disease)
Renal impairment (severely reduced kidney function)
Renal tubular disorder (disease of kidney tubules)
Acute hepatic failure
Chills (felling of cold)
Coma (state of unconsciousness lasting more than six hours)
Decreased appetite
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Asthma: 6 people, 17.14%
Pain: 6 people, 17.14%
Diarrhea: 5 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 14.29%
High Blood Cholesterol: 4 people, 11.43%
High Blood Pressure: 4 people, 11.43%
Bacterial Infection: 4 people, 11.43%
Nausea (feeling of having an urge to vomit): 4 people, 11.43%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 8.57%
Bipolar Disorder (mood disorder): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

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