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Atrovent and Simbrinza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atrovent (ipratropium bromide) and Simbrinza (brimonidine tartrate; brinzolamide). Common drug interactions include skin cancer among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Atrovent and Simbrinza. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Atrovent?

Atrovent has active ingredients of ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 33,210 Atrovent users. Check the latest studies of Atrovent.

What is Simbrinza?

Simbrinza has active ingredients of brimonidine tartrate; brinzolamide. It is often used in glaucoma. eHealthMe is studying from 4,543 Simbrinza users. Check the latest studies of Simbrinza.

On Jul, 17, 2026

15 people who take Atrovent and Simbrinza together, and have interactions are studied.

Atrovent and Simbrinza drug interactions.

What are the common drug interactions of Atrovent and Simbrinza, by gender? *:

female:

  1. Skin cancer
  2. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  3. Oxygen saturation decreased
  4. Chest pain
  5. Conjunctivitis (pink eye)
  6. Constipation
  7. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  8. Herpes zoster
  9. Ligament sprain (ligament stretched)
  10. Paralysis

male:

  1. Death

What are the common drug interactions of Atrovent and Simbrinza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Skin cancer
  2. Chest pain
  3. Herpes zoster
  4. Ligament sprain (ligament stretched)
  5. Urinary tract infection

60+:

  1. Colitis ulcerative (inflammation of colon with ulcer)
  2. Dizziness
  3. Conjunctivitis (pink eye)
  4. Death
  5. Paralysis
  6. Visual impairment
  7. Headache (pain in head)
  8. Infusion related reaction
  9. Pain
  10. Sinusitis (inflammation of sinus)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 33.33%
  2. Immunodeficiency Common Variable: 5 people, 33.33%
  3. Primary Immunodeficiency Syndrome: 3 people, 20.00%
  4. Urination - Excessive At Night: 1 person, 6.67%
  5. Hypersensitivity: 1 person, 6.67%
  6. Asthma: 1 person, 6.67%
  7. Chest Pain: 1 person, 6.67%
  8. Dyspnea (difficult or laboured breathing): 1 person, 6.67%
  9. Fever: 1 person, 6.67%
  10. High Blood Cholesterol: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Atrovent and Simbrinza?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Atrovent and Simbrinza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Atrovent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Simbrinza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atrovent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simbrinza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ipratropium bromide and brimonidine tartrate; brinzolamide (the active ingredients of Atrovent and Simbrinza, respectively), and Atrovent and Simbrinza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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