Atrovent and Spinraza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atrovent (ipratropium bromide) and Spinraza (nusinersen sodium). Common drug interactions include pneumonia among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Atrovent and Spinraza. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Atrovent?

Atrovent has active ingredients of ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 33,210 Atrovent users. Check the latest studies of Atrovent.

What is Spinraza?

Spinraza has active ingredients of nusinersen sodium. eHealthMe is studying from 7,063 Spinraza users. Check the latest studies of Spinraza.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 04, 2026

16 people who take Atrovent and Spinraza together, and have interactions are studied.

Atrovent and Spinraza drug interactions.

What are the common drug interactions of Atrovent and Spinraza, by gender? *:

female:

  1. Pneumonia
  2. Procedural pain
  3. Atrophy (wasting away of a part of the body)
  4. Body temperature decreased
  5. Bradycardia (abnormally slow heart action)
  6. Cardiac arrest
  7. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  8. Enzyme abnormality
  9. Gastrin secretion disorder (gastrin is produced at excessive levels)
  10. Heart rate decreased

male:

  1. Cardiac arrest
  2. Acute respiratory failure
  3. Post lumbar puncture syndrome
  4. Bronchial secretion retention
  5. Fluid retention (an abnormal accumulation of fluid in the blood)
  6. Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
  7. Inflammation
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  10. Oxygen saturation decreased

What are the common drug interactions of Atrovent and Spinraza, by age (0-1 to 60+)? *:

0-1:

  1. Atrophy (wasting away of a part of the body)
  2. Body temperature decreased
  3. Bradycardia (abnormally slow heart action)
  4. Cardiac arrest
  5. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  6. Enzyme abnormality
  7. Gastrin secretion disorder (gastrin is produced at excessive levels)
  8. Heart rate decreased
  9. Hyperhidrosis (abnormally increased sweating)
  10. Hypertension (high blood pressure)

2-9:

  1. Cardiac arrest
  2. Oxygen saturation decreased
  3. Decreased immune responsiveness
  4. Diarrhoea
  5. Enzyme abnormality
  6. Gastric haemorrhage (bleeding stomach)
  7. Gastrin secretion disorder (gastrin is produced at excessive levels)
  8. Gastritis (inflammation of stomach)
  9. Heart rate decreased
  10. Heart rate increased

10-19:

  1. Post lumbar puncture syndrome
  2. Spinal muscular atrophy (wasting of spinal muscles)
  3. Acute respiratory failure
  4. Chest discomfort
  5. Contrast media reaction (reaction associated with the use of intravenous contrast material during radiology)
  6. Drug ineffective
  7. Dyspnoea (difficult or laboured respiration)
  8. Ependymoma (tumour in the brain)
  9. Fluid retention (an abnormal accumulation of fluid in the blood)
  10. Gastrointestinal infection (infection of stomach and intestine)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Spinal Muscular Atrophy (wasting of spinal muscles): 15 people, 93.75%
  2. Respiratory Distress (difficulty in breathing): 5 people, 31.25%
  3. The Flu (the flu is caused by an influenza virus): 1 person, 6.25%
  4. Secretion Discharge: 1 person, 6.25%
  5. Flatulence (flatus expelled through the anus): 1 person, 6.25%
  6. Fever: 1 person, 6.25%
  7. Dyspnea (difficult or laboured breathing): 1 person, 6.25%
  8. Cough: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Atrovent and Spinraza?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Atrovent and Spinraza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Atrovent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Spinraza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atrovent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Spinraza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ipratropium bromide and nusinersen sodium (the active ingredients of Atrovent and Spinraza, respectively), and Atrovent and Spinraza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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