Atrovent and Xgeva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atrovent (ipratropium bromide) and Xgeva (denosumab). Common drug interactions include pallor among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Atrovent and Xgeva. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Atrovent?

Atrovent has active ingredients of ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 33,210 Atrovent users. Check the latest studies of Atrovent.

What is Xgeva?

Xgeva has active ingredients of denosumab. It is often used in breast cancer. eHealthMe is studying from 37,717 Xgeva users. Check the latest studies of Xgeva.

On Jul, 20, 2026

31 people who take Atrovent and Xgeva together, and have interactions are studied.

What are the common drug interactions of Atrovent and Xgeva, by gender? *:

female:

Pallor
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pelvic venous thrombosis (blood clot occurring inside a blood vessel and thromboses (dvts) that form in the deep veins of the legs or in the pelvic veins)
Pharyngeal inflammation
Pneumonia
Pyrexia (fever)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Thrombocytopenia (decrease of platelets in blood)

male:

Constipation
Malignant neoplasm progression (cancer tumour came back)
Abdominal distension
Abdominal pain
Asthenia (weakness)
Cardiac failure
Cardiac failure congestive
Chest discomfort
Coagulopathy (blood's ability to clot is impaired)
Cor pulmonale acute (rapid enlargement of the right ventricle of the heart)

What are the common drug interactions of Atrovent and Xgeva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Diarrhoea
Fatigue (feeling of tiredness)
Malignant neoplasm progression (cancer tumour came back)
Renal failure (kidney dysfunction)

40-49:

Cor pulmonale acute (rapid enlargement of the right ventricle of the heart)
Dyspnoea (difficult or laboured respiration)
Hepatitis (inflammation of the liver)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Pharyngeal inflammation
Thrombocytopenia (decrease of platelets in blood)
Pulmonary oedema (fluid accumulation in the lungs)
Tumour haemorrhage (bleeding from tumour)
C-reactive protein increased
White blood cell count increased

50-59:

Anaemia (lack of blood)
Asthenia (weakness)
Chest pain
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Enterocolonic fistula
Fatigue (feeling of tiredness)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypokalaemia (low potassium)
Large intestine perforation (hole in large intestine)

60+:

Malignant neoplasm progression (cancer tumour came back)
Arthralgia (joint pain)
Oxygen saturation decreased
Pain in extremity
Photopsia (presence of perceived flashes of light)
Anaemia of chronic disease
Breast cancer stage iv
Chest pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 8 people, 25.81%
Pain: 6 people, 19.35%
Dyspnea (difficult or laboured breathing): 5 people, 16.13%
Breast Cancer Metastatic: 4 people, 12.90%
Multiple Myeloma (cancer of the plasma cells): 4 people, 12.90%
Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 12.90%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 9.68%
Cancer Pain: 3 people, 9.68%
Cough: 3 people, 9.68%
Anaemia (lack of blood): 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

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