Augmentin '125' and Adalat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin '125' (amoxicillin; clavulanate potassium) and Adalat (nifedipine). Common drug interactions include ataxia among females and bradycardia neonatal among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin '125' and Adalat. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin '125'?

Augmentin '125' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 10,452 Augmentin '125' users. Check the latest studies of Augmentin '125'.

What is Adalat?

Adalat has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 20,940 Adalat users. Check the latest studies of Adalat.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

23 people who take Augmentin '125' and Adalat together, and have interactions are studied.

Augmentin '125' and Adalat drug interactions.

What are the common drug interactions of Augmentin '125' and Adalat, by gender? *:

female:

Ataxia (loss of full control of bodily movements)
Drug exposure during pregnancy
Dysarthria (speech disorder)
Psychomotor skills impaired
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Alanine aminotransferase increased
Alopecia (absence of hair from areas of the body)
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Arrhythmia (irregular heartbeat)
Aspartate aminotransferase increased

male:

Bradycardia neonatal (sinus rhythm with a heart rate below the normal limit in newborn)
Drug exposure during pregnancy
Pneumocystis carinii pneumonia (pneumonia occurring in infants or in persons with impaired immune systems)
Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
Renal failure acute (rapid kidney dysfunction)
Vomiting
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Acute respiratory distress syndrome
Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
Apgar score low

What are the common drug interactions of Augmentin '125' and Adalat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Cholestasis of pregnancy (normal flow of bile in the gallbladder is affected by the high amounts of pregnancy hormones)
Drug exposure during pregnancy
Hepatic enzyme increased
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

30-39:

Acute pulmonary oedema (sudden deposit of fluid in the lung))
Diarrhoea
Drug exposure during pregnancy
Flushing (the warm, red condition of human skin)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Myocarditis (inflammation of heart muscle myocardium)
Oedema peripheral (superficial swelling)
Pleural effusion (water on the lungs)
Respiratory distress (difficulty in breathing)
Ureteric stenosis (abnormal narrowing or contraction of a duct or canal)

40-49:

Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Arrhythmia (irregular heartbeat)
Cardiac valve disease (heart valve disease)
Carotid artery stenosis (narrowing of carotid artery)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Chronic fatigue syndrome (disorder that causes extreme fatigue)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dyspepsia (indigestion)
Gallbladder disorder

50-59:

Asthenia (weakness)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Pruritus (severe itching of the skin)
Rash
Renal failure (kidney dysfunction)
Skin induration (an abnormally hard spot or area on the skin)
Type iv hypersensitivity reaction (delayed type hypersensitivity as the reaction takes two to three days to develop)
Urticaria (rash of round, red welts on the skin that itch intensely)

60+:

Abdominal pain
Ataxia (loss of full control of bodily movements)
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Acute respiratory distress syndrome
Alopecia (absence of hair from areas of the body)
Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
Atrioventricular block complete (heart block complete)
Bradycardia (abnormally slow heart action)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Cardiomyopathy (weakening of the heart muscle)

What are the existing conditions these people have? *

Threatened Labor: 4 people, 17.39%
Sigmoiditis (inflammation of the sigmoid colon): 2 people, 8.70%
Erysipelas (bacterial skin infection): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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