Augmentin '125' and Etoposide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin '125' (amoxicillin; clavulanate potassium) and Etoposide (etoposide). Common drug interactions include somnolence among females and febrile bone marrow aplasia among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin '125' and Etoposide. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin '125'?

Augmentin '125' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 10,452 Augmentin '125' users. Check the latest studies of Augmentin '125'.

What is Etoposide?

Etoposide has active ingredients of etoposide. eHealthMe is studying from 77,815 Etoposide users. Check the latest studies of Etoposide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

33 people who take Augmentin '125' and Etoposide together, and have interactions are studied.

Augmentin '125' and Etoposide drug interactions.

What are the common drug interactions of Augmentin '125' and Etoposide, by gender? *:

female:

Somnolence (a state of near-sleep, a strong desire for sleep)
Stem cell transplant
Stomatitis (inflammation of mucous membrane of mouth)
White blood cell count decreased
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Bone marrow failure
Chills (felling of cold)
Colitis ulcerative (inflammation of colon with ulcer)

male:

Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
Ileitis (inflammation of the ileum)
Chest discomfort
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Haematocrit decreased
Oesophagitis (inflammation of oesophagus)
Oral intake reduced
Pruritus (severe itching of the skin)

What are the common drug interactions of Augmentin '125' and Etoposide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Respiratory tract infection fungal
Staphylococcal infection (an infection with staphylococcus bacteria)
Streptococcal infection
Vomiting
White blood cell count decreased
Atelectasis (partial or complete collapse of the lung)
Bacteraemia (presence of bacteria in the blood)
Caecitis (inflammation of the cecum)
Chemical eye injury
Constipation

20-29:

Acute pulmonary oedema (sudden deposit of fluid in the lung))
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Colitis ulcerative (inflammation of colon with ulcer)
Anaemia (lack of blood)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dyspnoea (difficult or laboured respiration)
Hypoxia (low oxygen in tissues)
Interstitial lung disease
Neutropenia (an abnormally low number of neutrophils)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)

30-39:

Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
Ileitis (inflammation of the ileum)
Intestinal obstruction
Jejunitis (inflammation of the jejunum of the small intestine)

40-49:

Haematemesis (vomiting of blood)

50-59:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia
Renal impairment (severely reduced kidney function)
Abdominal distension
Abdominal pain
Abdominal pain upper
Acquired immunodeficiency syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv))
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)

60+:

Pyrexia (fever)
Chills (felling of cold)
Fatigue (feeling of tiredness)
Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
Haemoglobin decreased
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Oesophagitis (inflammation of oesophagus)
Oral intake reduced
Productive cough
Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 9 people, 27.27%
Pain: 8 people, 24.24%
Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 2 people, 6.06%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 6.06%
Nausea And Vomiting: 2 people, 6.06%
Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 2 people, 6.06%
Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 2 people, 6.06%
Burkitt's Lymphoma (cancer of the lymphatic system): 2 people, 6.06%
Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 6.06%
Brain Neoplasm (tumour of brain): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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