Augmentin '125' and Truvada drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Augmentin '125' (amoxicillin; clavulanate potassium) and Truvada (emtricitabine; tenofovir disoproxil fumarate). Common drug interactions include adrenal insufficiency among females and oedema peripheral among males.
The phase IV clinical study analyzes what interactions people have when they take Augmentin '125' and Truvada. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Augmentin '125'?
Augmentin '125' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 10,452 Augmentin '125' users. Check the latest studies of Augmentin '125'.
What is Truvada?
Truvada has active ingredients of emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 76,246 Truvada users. Check the latest studies of Truvada.
18 people who take Augmentin '125' and Truvada together, and have interactions are studied.

What are the common drug interactions of Augmentin '125' and Truvada, by gender? *:
female:
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Ascites (accumulation of fluid in the abdominal cavity)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Cushing's syndrome (obesity, a rounded face, increased fat)
- Abscess oral (abscess in the mouth)
- Acquired oesophageal web (structural abnormalities in the oesophagus)
- Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
- Agitation (state of anxiety or nervous excitement)
- Antinuclear antibody positive
- Arthralgia (joint pain)
male:
- Oedema peripheral (superficial swelling)
- Cardiac arrest
- Blood glucose increased
- Blood sodium decreased
- Blood triglycerides increased
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Pyrexia (fever)
- Renal impairment (severely reduced kidney function)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
What are the common drug interactions of Augmentin '125' and Truvada, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Agitation (state of anxiety or nervous excitement)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
- Insomnia (sleeplessness)
- Pruritus (severe itching of the skin)
- Rash
- Rash papular (redness with papule)
- Urticaria (rash of round, red welts on the skin that itch intensely)
20-29:
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Blood triglycerides increased
- Pyrexia (fever)
- Renal failure (kidney dysfunction)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
30-39:
n/a
40-49:
- Cardiac arrest
- Electrocardiogram qt prolonged
- Fall
- Humerus fracture (injury to the upper arm bone)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
50-59:
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Renal impairment (severely reduced kidney function)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Abscess oral (abscess in the mouth)
- Acquired oesophageal web (structural abnormalities in the oesophagus)
- Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
- Antinuclear antibody positive
- Arthralgia (joint pain)
- Asthma
- Back pain
60+:
- Oedema peripheral (superficial swelling)
- Renal failure (kidney dysfunction)
What are the existing conditions these people have? *
- Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 3 people, 16.67%
- Lower Respiratory Tract Infection: 3 people, 16.67%
- Seasonal Allergy (allergic condition due to certain season): 2 people, 11.11%
- Pharyngolaryngeal Pain: 2 people, 11.11%
- Drug Dependence: 2 people, 11.11%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 11.11%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.56%
- Pain: 1 person, 5.56%
- Otitis Media Acute (rapid inflammation of the middle ear): 1 person, 5.56%
- Nasal Polyps (masses that develop in the lining of the nose): 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Augmentin '125' and Truvada?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Augmentin '125' (10,452 reports)
- Truvada (76,246 reports)
Browse all drug interactions of Augmentin '125' and Truvada:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Augmentin '125':
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Truvada:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Augmentin '125' and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Truvada and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium and emtricitabine; tenofovir disoproxil fumarate (the active ingredients of Augmentin '125' and Truvada, respectively), and Augmentin '125' and Truvada (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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