Augmentin '500' and Tylenol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin '500' (amoxicillin; clavulanate potassium) and Tylenol (acetaminophen). Common drug interactions include depression among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin '500' and Tylenol. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin '500'?

Augmentin '500' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 509 Augmentin '500' users. Check the latest studies of Augmentin '500'.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,310 Tylenol users. Check the latest studies of Tylenol.

On Aug, 10, 2026

17 people who take Augmentin '500' and Tylenol together, and have interactions are studied.

Augmentin '500' and Tylenol drug interactions.

What are the common drug interactions of Augmentin '500' and Tylenol, by gender? *:

female:

Depression
Vomiting
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal pain upper
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Diarrhoea
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypercholesterolaemia (high levels of cholesterol in the blood)

male:

Chest pain
Dyspnoea (difficult or laboured respiration)
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Aspartate aminotransferase increased
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blood alkaline phosphatase increased
Bone disorder

What are the common drug interactions of Augmentin '500' and Tylenol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Dyspnoea (difficult or laboured respiration)
Pain in extremity
Maternal exposure during pregnancy (use of substance during pregnancy)
Polyhydramnios (excess of amniotic fluid in the amniotic sac)
Abdominal pain
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)

40-49:

Ageusia (loss of taste functions of the tongue)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Dyspnoea (difficult or laboured respiration)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Tendon disorder (disease of tendon)
Tendonitis (a condition that causes pain and swelling of tendons)
Anaemia (lack of blood)
Bile duct stone

50-59:

Blood urea increased
Cervicitis (inflammation of the uterine cervix)
Depression
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Haematuria (presence of blood in urine)
Impaired healing
Malaise (a feeling of general discomfort or uneasiness)
Micturition urgency (urgency to pass the urine)
Myalgia (muscle pain)

60+:

Abdominal hernia
Abscess oral (abscess in the mouth)
Back pain
Bone disorder
Bone neoplasm malignant (cancer of bone)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Carotid bruit (sound heard over the carotid artery area during auscultation)
Cerumen impaction

What are the existing conditions these people have? *

Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 2 people, 11.76%
Anaemia (lack of blood): 2 people, 11.76%
Osteomyelitis (infection of bone): 2 people, 11.76%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 11.76%
Metastases To Bone (cancer spreads to bone): 2 people, 11.76%
Menopause (end of monthly cycles in women): 2 people, 11.76%
High Blood Pressure: 2 people, 11.76%
Upper Respiratory Tract Infection: 1 person, 5.88%
Hypersensitivity: 1 person, 5.88%
Asthma: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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