Augmentin and Cleocin hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Cleocin hydrochloride (clindamycin hydrochloride). Common drug interactions include pleural effusion among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Cleocin hydrochloride. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Cleocin hydrochloride?

Cleocin hydrochloride has active ingredients of clindamycin hydrochloride. It is often used in infection. eHealthMe is studying from 441 Cleocin hydrochloride users. Check the latest studies of Cleocin hydrochloride.

On Aug, 07, 2026

27 people who take Augmentin and Cleocin hydrochloride together, and have interactions are studied.

Augmentin and Cleocin hydrochloride drug interactions.

What are the common drug interactions of Augmentin and Cleocin Hydrochloride, by gender? *:

female:

Pleural effusion (water on the lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)
Swelling face
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Bone disorder
Cellulitis (infection under the skin)
Deafness
Hypotension (abnormally low blood pressure)
Joint dislocation (a joint position is changed from normal position)
Osteopenia (a condition where bone mineral density is lower than normal)

male:

Anaemia (lack of blood)
Anxiety
Intervertebral disc degeneration (spinal disc degeneration)
Lymphadenopathy (disease or enlargement of lymph nodes)
Metastases to bone (cancer spreads to bone)
Multiple myeloma (cancer of the plasma cells)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Neuropathy peripheral (surface nerve damage)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteomyelitis (infection of bone)

What are the common drug interactions of Augmentin and Cleocin Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cholecystitis chronic (long lasting infection of gallbladder)
Pain
Pancreatitis (inflammation of pancreas)
Cardiac disorder
Migraine (headache)
Type 1 diabetes mellitus

30-39:

n/a

40-49:

Activities of daily living impaired
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Adrenal disorder
Anxiety
Arthralgia (joint pain)
Arthropathy
Atelectasis (partial or complete collapse of the lung)
Bone cyst
Bone loss
Cardiac failure congestive

50-59:

Hypotension (abnormally low blood pressure)
Joint dislocation (a joint position is changed from normal position)
Osteolysis (dissolution of bone)
Osteomyelitis (infection of bone)
Osteonecrosis of jaw (death of bone of jaw)
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Pain in jaw
Pleural effusion (water on the lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

Anaemia (lack of blood)
Anxiety
Intervertebral disc degeneration (spinal disc degeneration)
Lymphadenopathy (disease or enlargement of lymph nodes)
Metastases to bone (cancer spreads to bone)
Multiple myeloma (cancer of the plasma cells)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Neuropathy peripheral (surface nerve damage)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteomyelitis (infection of bone)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 17 people, 62.96%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 8 people, 29.63%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 4 people, 14.81%
Thrombocytopenia (decrease of platelets in blood): 3 people, 11.11%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 11.11%
Osteoporosis (bones weak and more likely to break): 3 people, 11.11%
Pain: 2 people, 7.41%
Birth Control: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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