Augmentin and Co-codamol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Co-codamol (acetaminophen; codeine phosphate). Common drug interactions include aortic aneurysm among females and viral upper respiratory tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Co-codamol. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Co-codamol?

Co-codamol has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 2,364 Co-codamol users. Check the latest studies of Co-codamol.

On Jul, 09, 2026

20 people who take Augmentin and Co-codamol together, and have interactions are studied.

Augmentin and Co-codamol drug interactions.

What are the common drug interactions of Augmentin and Co-Codamol, by gender? *:

female:

Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Asthenia (weakness)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Contusion (a type of hematoma of tissue in which capillaries)
Dyspnoea (difficult or laboured respiration)
Faeces discoloured
Haemorrhage (bleeding)
Malaise (a feeling of general discomfort or uneasiness)

male:

Viral upper respiratory tract infection
Injection site erythema (redness at injection site)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Depressed level of consciousness
Epistaxis (bleed from the nose)
Escherichia infection (bacterial infection by escherichia coli)
Fall
Frequent bowel movements
Headache (pain in head)
Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the common drug interactions of Augmentin and Co-Codamol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Bladder spasm
Epistaxis (bleed from the nose)
Headache (pain in head)
Influenza like illness
Pneumonia

50-59:

Viral upper respiratory tract infection
Erythema infectiosum (infection that results in a mild rash on the face, trunk, and limbs)
Febrile neutropenia (fever with reduced white blood cells)
Ankle fracture
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Depressed level of consciousness
Escherichia infection (bacterial infection by escherichia coli)
Fall
Impaired healing
Oxygen saturation decreased

60+:

Injection site erythema (redness at injection site)
Rash
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypophagia (reduced food intake)
Hypotension (abnormally low blood pressure)
Lethargy (tiredness)
Pruritus (severe itching of the skin)
Urine output decreased
Haematemesis (vomiting of blood)
Abdominal pain

What are the existing conditions these people have? *

Lower Respiratory Tract Infection: 8 people, 40.00%
Abdominal Pain: 6 people, 30.00%
Abdominal Pain Upper: 6 people, 30.00%
Anaemia (lack of blood): 6 people, 30.00%
Nausea (feeling of having an urge to vomit): 6 people, 30.00%
Chest Pain: 6 people, 30.00%
Multiple Myeloma (cancer of the plasma cells): 4 people, 20.00%
Back Pain: 3 people, 15.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.00%
Gastric Ulcer (stomach ulcer): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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