Augmentin and Enulose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Enulose (lactulose). Common drug interactions include musculoskeletal pain among females and drug intolerance among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Enulose. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Enulose?

Enulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 711 Enulose users. Check the latest studies of Enulose.

On Jul, 08, 2026

18 people who take Augmentin and Enulose together, and have interactions are studied.

Augmentin and Enulose drug interactions.

What are the common drug interactions of Augmentin and Enulose, by gender? *:

female:

Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Non-cardiac chest pain
Oedema peripheral (superficial swelling)
Abdominal tenderness
Anaemia (lack of blood)
Anaemia macrocytic (a macrocytic class of anaemia)
Anal sphincter atony (anal muscles are weak and cannot ensure an efficient sealing, this is called a sphincter atony)
Antinuclear antibody positive
Anxiety
Aphasia (damage to the parts of the brain that control language)

male:

Drug intolerance (drug sensitivity)
Agitation (state of anxiety or nervous excitement)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Abdominal pain
Anaemia (lack of blood)
Aspartate aminotransferase increased
Blood bilirubin increased
Cardiac arrest
Chronic hepatic failure (long lasting liver failure)

What are the common drug interactions of Augmentin and Enulose, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Agitation (state of anxiety or nervous excitement)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Drug intolerance (drug sensitivity)
Fall
Infusion related reaction
Lymphadenopathy (disease or enlargement of lymph nodes)
Pyrexia (fever)
Rash
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

30-39:

n/a

40-49:

Abdominal pain
Memory impairment
Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)
Aspartate aminotransferase increased
Blood bilirubin increased
Cardiac arrest
Chronic hepatic failure (long lasting liver failure)
Cirrhosis alcoholic (chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue caused by alcoholism)
Coagulopathy (blood's ability to clot is impaired)

50-59:

Injury
Insomnia (sleeplessness)
Interstitial lung disease
Large intestinal ulcer
Light chain analysis increased
Localised infection (infection at the single location)
Monoclonal gammopathy
Mood altered (changes in mood)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nausea (feeling of having an urge to vomit)

60+:

Confusional state
Death
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Balance disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Dizziness

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 27.78%
Immunodeficiency Common Variable: 4 people, 22.22%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 16.67%
Pain: 3 people, 16.67%
Nausea (feeling of having an urge to vomit): 2 people, 11.11%
Indigestion: 2 people, 11.11%
Cough: 2 people, 11.11%
Nausea And Vomiting: 2 people, 11.11%
High Blood Pressure: 2 people, 11.11%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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