Augmentin and Flector drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Flector (diclofenac epolamine). Common drug interactions include fatigue among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Flector. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Flector?

Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 5,112 Flector users. Check the latest studies of Flector.

On Jul, 10, 2026

60 people who take Augmentin and Flector together, and have interactions are studied.

Augmentin and Flector drug interactions.

What are the common drug interactions of Augmentin and Flector, by gender? *:

female:

Fatigue (feeling of tiredness)
Neck pain
Pain in extremity
Visual impairment
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Chest pain
Dehydration (dryness resulting from the removal of water)
Delirium (wild excitement)
Dementia (madness)

male:

Pyrexia (fever)
Leukocytosis (increased white blood cells)
Skin exfoliation (removal of the oldest dead skin cells)
Skin lesion
Toxic skin eruption (skin breakdown due to toxic substance)
Urinary tract infection staphylococcal
Weight increased
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Intestinal perforation (complete penetration of the wall of the intestine)

What are the common drug interactions of Augmentin and Flector, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Headache (pain in head)
Abdominal pain
Activities of daily living impaired
Arthralgia (joint pain)
Asthenia (weakness)
Chills (felling of cold)
Conjunctivitis (pink eye)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Drug intolerance (drug sensitivity)

50-59:

General physical health deterioration (weak health status)
Hyperthyroidism (over activity of the thyroid gland)
Lung disorder (lung disease)
Malignant neoplasm progression (cancer tumour came back)
Mucosal inflammation (infection of mucous membrane)
Nausea (feeling of having an urge to vomit)
Neck pain
Somnolence (a state of near-sleep, a strong desire for sleep)
Thrombocytopenia (decrease of platelets in blood)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

60+:

Depression
Fatigue (feeling of tiredness)
Diarrhoea
Dry mouth
Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Hallucination (an experience involving the perception of something not present)
Hyperhidrosis (abnormally increased sweating)
Joint swelling
Muscular weakness (muscle weakness)

What are the existing conditions these people have? *

Pneumonia: 9 people, 15.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 13.33%
Lung Neoplasm Malignant (cancer tumour of lung): 7 people, 11.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 11.67%
Depression: 7 people, 11.67%
High Blood Pressure: 6 people, 10.00%
Asthma: 5 people, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 8.33%
Lung Disorder (lung disease): 5 people, 8.33%
Lung Infection: 5 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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