Augmentin and Florinef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Florinef (fludrocortisone acetate). Common drug interactions include neuropathy peripheral among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Florinef. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Florinef?

Florinef has active ingredients of fludrocortisone acetate. It is often used in addison's disease. eHealthMe is studying from 3,834 Florinef users. Check the latest studies of Florinef.

On Jul, 27, 2026

66 people who take Augmentin and Florinef together, and have interactions are studied.

Augmentin and Florinef drug interactions.

What are the common drug interactions of Augmentin and Florinef, by gender? *:

female:

Neuropathy peripheral (surface nerve damage)
Decreased appetite
Gait disturbance
Osteonecrosis of jaw (death of bone of jaw)
Arthralgia (joint pain)
Asthenia (weakness)
Depression
Hypoaesthesia (reduced sense of touch or sensation)
Joint dislocation (a joint position is changed from normal position)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

male:

Confusional state
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Asthenia (weakness)
Asthma
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Depression
Dizziness
Head injury
Headache (pain in head)
Hepatitis (inflammation of the liver)

What are the common drug interactions of Augmentin and Florinef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal distension
Drug administration error
Flatulence (flatus expelled through the anus)

30-39:

Pain

40-49:

n/a

50-59:

Renal failure chronic (long lasting kidney dysfunction)
Neuropathy peripheral (surface nerve damage)
Decreased appetite
Gait disturbance
Osteonecrosis of jaw (death of bone of jaw)
Joint dislocation (a joint position is changed from normal position)
Pain in extremity
Spinal compression fracture (fracture due to spinal compression on bone)
Adrenal neoplasm (abnormal growth of adrenal gland)
Anaemia (lack of blood)

60+:

Confusional state
Facial pain
Hypoaesthesia (reduced sense of touch or sensation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Anaemia (lack of blood)
Anxiety
Asthma
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Dizziness
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 32 people, 48.48%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 17 people, 25.76%
Light Chain Analysis Increased: 12 people, 18.18%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 12 people, 18.18%
Neoplasm Malignant (cancer tumour): 8 people, 12.12%

* Approximation only. Some reports may have incomplete information.

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