Augmentin and Glucovance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Glucovance (glyburide; metformin hydrochloride). Common drug interactions include pain in jaw among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Glucovance. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Glucovance?

Glucovance has active ingredients of glyburide; metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 6,302 Glucovance users. Check the latest studies of Glucovance.

On Jul, 27, 2026

56 people who take Augmentin and Glucovance together, and have interactions are studied.

Augmentin and Glucovance drug interactions.

What are the common drug interactions of Augmentin and Glucovance, by gender? *:

female:

Pain in jaw
Pneumonia
Cardiomegaly (increased size of heart than normal)
Cellulitis (infection under the skin)
Dyspnoea (difficult or laboured respiration)
Oral candidiasis (fungal infection of mouth)
Pyrexia (fever)
Rash
Skin lesion
Anxiety

male:

Pain
Anaemia (lack of blood)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Loss of consciousness
Syncope (loss of consciousness with an inability to maintain postural tone)
Fatigue (feeling of tiredness)
Hot flush (sudden feelings of heat)
Confusional state
Facial pain

What are the common drug interactions of Augmentin and Glucovance, by age (0-1 to 60+)? *:

0-1:

Anaemia neonatal
Blood creatinine increased
Blood urea increased
Cholesteatoma (abnormal skin growth in the middle ear behind the eardrum)
Conjunctivitis (pink eye)
Craniosynostosis (a baby is born with an abnormally shaped skull or develops one during growth)
Deafness
Foetal distress syndrome (altered heart rate or rhythm and leading tocompromised blood flow or changes in blood chemistry of foetus)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Hyperbilirubinaemia neonatal (excess of bilirubin in the blood in newborn)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Abscess neck (neck abscesses)
Accommodation disorder
Adenomyosis (presence of ectopic glandular tissue found in muscle)
Altered state of consciousness (altered state of mind)
Altered visual depth perception
Anaemia (lack of blood)
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Arthropathy

50-59:

Chronic kidney disease
Gamma-glutamyltransferase increased
Generalised erythema (redness of the skin all over the body)
Hepatic steatosis (fatty liver disease)
Hepatitis (inflammation of the liver)
Injury
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Osteonecrosis (death of bone)
Pain
Renal failure (kidney dysfunction)

60+:

Anxiety
Pain
Osteomyelitis (infection of bone)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Asthenia (weakness)
Dizziness
Hypoaesthesia (reduced sense of touch or sensation)
Loss of consciousness
Syncope (loss of consciousness with an inability to maintain postural tone)
Facial pain

What are the existing conditions these people have? *

High Blood Pressure: 23 people, 41.07%
Depression: 23 people, 41.07%
Breast Cancer: 20 people, 35.71%
Metastases To Bone (cancer spreads to bone): 19 people, 33.93%
Bone Pain: 19 people, 33.93%
Sleep Disorder: 7 people, 12.50%
Osteolysis (dissolution of bone): 5 people, 8.93%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 7.14%
Resorption Bone Increased: 4 people, 7.14%
Pelvic Discomfort: 4 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and Glucovance?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously