Augmentin and Ketalar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Ketalar (ketamine hydrochloride). Common drug interactions include cellulitis among females and bronchospasm among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Ketalar. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Ketalar?

Ketalar has active ingredients of ketamine hydrochloride. eHealthMe is studying from 1,226 Ketalar users. Check the latest studies of Ketalar.

On Jul, 10, 2026

15 people who take Augmentin and Ketalar together, and have interactions are studied.

Augmentin and Ketalar drug interactions.

What are the common drug interactions of Augmentin and Ketalar, by gender? *:

female:

Cellulitis (infection under the skin)
Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Gangrene (body tissue dies)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Perineal abscess
Sepsis (a severe blood infection that can lead to organ failure and death)
Vulval abscess
Vulval cellulitis (inflammation of skin around vagina)
Vulvitis (inflammation of the vulva)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)

male:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Blood alkaline phosphatase decreased
Blood bilirubin increased
Blood lactate dehydrogenase decreased
Blood pressure decreased
Bradycardia (abnormally slow heart action)
Circulatory collapse
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Heart rate increased

What are the common drug interactions of Augmentin and Ketalar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pyrexia (fever)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

20-29:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Respiratory failure (inadequate gas exchange by the respiratory system)

30-39:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Generalised erythema (redness of the skin all over the body)
Pancreatitis (inflammation of pancreas)
Anaesthetic complication
Blood albumin decreased
Blood alkaline phosphatase decreased
Blood bilirubin increased
Blood lactate dehydrogenase decreased
Blood pressure decreased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

40-49:

Cellulitis (infection under the skin)
Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Gangrene (body tissue dies)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Perineal abscess
Sepsis (a severe blood infection that can lead to organ failure and death)
Vulval abscess
Vulval cellulitis (inflammation of skin around vagina)
Vulvitis (inflammation of the vulva)
Anal abscess

50-59:

Hypotension (abnormally low blood pressure)
Ill-defined disorder
Oxygen saturation decreased
Pallor
Respiratory disorder (respiratory disease)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Urticaria (rash of round, red welts on the skin that itch intensely)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Blood pressure decreased
Circulatory collapse

60+:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Bradycardia (abnormally slow heart action)
Circulatory collapse
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Generalised erythema (redness of the skin all over the body)

What are the existing conditions these people have? *

Hypotension (abnormally low blood pressure): 5 people, 33.33%
Weight Decreased: 3 people, 20.00%
Anaesthesia: 3 people, 20.00%
Type 2 Diabetes: 3 people, 20.00%
High Blood Pressure: 3 people, 20.00%
Pain: 3 people, 20.00%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 13.33%
Hypokalemia (low potassium): 2 people, 13.33%
Hypersensitivity: 2 people, 13.33%
Haemostasis (stopping of bleeding): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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