Augmentin and Megestrol acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Megestrol acetate (megestrol acetate). Common drug interactions include deep vein thrombosis among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Megestrol acetate. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Megestrol acetate?

Megestrol acetate has active ingredients of megestrol acetate. It is often used in appetite - decreased. eHealthMe is studying from 5,427 Megestrol acetate users. Check the latest studies of Megestrol acetate.

On Jul, 20, 2026

59 people who take Augmentin and Megestrol acetate together, and have interactions are studied.

Augmentin and Megestrol acetate drug interactions.

What are the common drug interactions of Augmentin and Megestrol Acetate, by gender? *:

female:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gait disturbance
Oedema peripheral (superficial swelling)
Alanine aminotransferase increased
Anxiety
Ascites (accumulation of fluid in the abdominal cavity)
Bone disorder
Breast cancer metastatic
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Constipation

male:

Pneumonia
Vomiting
Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
Fall
Nausea (feeling of having an urge to vomit)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Abdominal pain upper
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiomegaly (increased size of heart than normal)

What are the common drug interactions of Augmentin and Megestrol Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Death
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

30-39:

n/a

40-49:

Arthralgia (joint pain)
Agitation (state of anxiety or nervous excitement)
Asthenia (weakness)
Confusion
Dysphagia (a condition in which swallowing is difficult or painful)
Face oedema (swelling of face)
Haemorrhage (bleeding)
Hypertension (high blood pressure)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Oral candidiasis (fungal infection of mouth)

50-59:

Abdominal pain upper
Acquired oesophageal web (structural abnormalities in the oesophagus)
Anxiety
Back pain
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Chills (felling of cold)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
Colonic polyp (extra part of colon tissue grow in intestine)

60+:

Pneumonia
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Neuropathy peripheral (surface nerve damage)
Pain
Rash
Septic shock (shock due to blood infection)
Anaemia (lack of blood)
Arteriosclerosis (thickening and hardening of arteries)
Asthenia (weakness)
Asthma

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 12 people, 20.34%
Pain: 10 people, 16.95%
Constipation: 8 people, 13.56%
High Blood Pressure: 7 people, 11.86%
Stress And Anxiety: 5 people, 8.47%
Breast Cancer: 5 people, 8.47%
Prostate Cancer Metastatic: 5 people, 8.47%
Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 5 people, 8.47%
Fever: 4 people, 6.78%
Periodontitis (inflammation of the tissue around the teeth): 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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