Augmentin and Nuvaring drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Nuvaring (ethinyl estradiol; etonogestrel). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Nuvaring. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Nuvaring?

Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,730 Nuvaring users. Check the latest studies of Nuvaring.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

53 people who take Augmentin and Nuvaring together, and have interactions are studied.

Augmentin and Nuvaring drug interactions.

What are the common drug interactions of Augmentin and Nuvaring, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Headache (pain in head)
  3. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  4. Abortion spontaneous (naturally occurring miscarriage)
  5. Anxiety
  6. Abortion missed (delayed or silent miscarriage)
  7. Blood iron decreased
  8. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  9. Drug exposure during pregnancy
  10. Fall

male:

n/a

What are the common drug interactions of Augmentin and Nuvaring, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Abortion missed (delayed or silent miscarriage)
  3. Drug exposure during pregnancy
  4. Blood thyroid stimulating hormone decreased
  5. Coagulation factor viii level increased
  6. Hepatosplenomegaly (enlargement of both the liver and the spleen)
  7. Human papilloma virus test positive
  8. Intra-uterine death
  9. Local swelling (swelling at the site of some application of substance or injury)
  10. Proteinuria (presence of protein in the urine)

20-29:

  1. Transverse sinus thrombosis (a blood clot in transverse sinus)
  2. Acne cystic (skin problems that cause pimples)
  3. Antinuclear antibody positive
  4. Antiphospholipid antibodies positive
  5. Benign intracranial hypertension (benign intracranial hypertension (bih) is a headache syndrome)
  6. Cardiolipin antibody positive
  7. Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
  8. Chest discomfort
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  10. Cough

30-39:

  1. Blood iron decreased
  2. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  3. Fall
  4. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  5. Headache (pain in head)
  6. Viral infection
  7. Vulval cellulitis (inflammation of skin around vagina)
  8. Wheezing (a high-pitched whistling sound made while you breath)
  9. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  10. Pain

40-49:

  1. Anxiety
  2. Aphonia (inability to produce voice)
  3. Emotional distress
  4. Faeces hard
  5. Fatigue (feeling of tiredness)
  6. Foot deformity (functional disability of foot)
  7. Glomerular filtration rate decreased
  8. High density lipoprotein increased
  9. Homeless
  10. Infusion site haemorrhage (bleeding from infusion site)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 16.98%
  2. Immunodeficiency Common Variable: 8 people, 15.09%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 13.21%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 13.21%
  5. Menstruation Irregular: 4 people, 7.55%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and Nuvaring?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Augmentin and Nuvaring:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nuvaring:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Augmentin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nuvaring and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium and ethinyl estradiol; etonogestrel (the active ingredients of Augmentin and Nuvaring, respectively), and Augmentin and Nuvaring (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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