Augmentin and Patanol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Patanol (olopatadine hydrochloride). Common drug interactions include pain among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Augmentin and Patanol. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.
What is Augmentin?
Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.
What is Patanol?
Patanol has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,339 Patanol users. Check the latest studies of Patanol.
79 people who take Augmentin and Patanol together, and have interactions are studied.

What are the common drug interactions of Augmentin and Patanol, by gender? *:
female:
- Pain
- Arthralgia (joint pain)
- Depression
- Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
- Thermal burn (burn by heat)
- Fatigue (feeling of tiredness)
- Oedema peripheral (superficial swelling)
- Pain in extremity
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Chest pain
male:
- Renal failure (kidney dysfunction)
- Diarrhoea
- Osteomyelitis chronic (long lasting infection of bone marrow)
- Pain
- Abdominal pain upper
- Anaemia (lack of blood)
- Aortic arteriosclerosis (hardening of the aortic arteries)
- Aortic dilatation
- Asthenia (weakness)
- Dizziness
What are the common drug interactions of Augmentin and Patanol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
- Death
30-39:
- Abdominal pain
- Anal fissure
- Constipation
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Depression
- Diarrhoea
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Gastric hypermotility (over activity of the stomach)
- Gastritis (inflammation of stomach)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
40-49:
- Pruritus (severe itching of the skin)
- Rash
- Weight increased
- Malaise (a feeling of general discomfort or uneasiness)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
- Thermal burn (burn by heat)
- Depression
- Pain
- Anxiety
50-59:
- Renal failure (kidney dysfunction)
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
- Thrombosis (formation of a blood clot inside a blood vessel)
- Headache (pain in head)
- Hepatitis (inflammation of the liver)
- Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Insomnia (sleeplessness)
- Jaundice cholestatic
- Nephrogenic anaemia (anaemia due to kidney disease)
60+:
- Renal failure (kidney dysfunction)
- Pain
- Emotional distress
- Gait disturbance
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- General physical health deterioration (weak health status)
- Hypophagia (reduced food intake)
- Malaise (a feeling of general discomfort or uneasiness)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
What are the existing conditions these people have? *
- Pain: 21 people, 26.58%
- Immunodeficiency Common Variable: 17 people, 21.52%
- Multiple Myeloma (cancer of the plasma cells): 10 people, 12.66%
- High Blood Pressure: 9 people, 11.39%
- High Blood Cholesterol: 9 people, 11.39%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 10.13%
- Cardiac Disorder: 8 people, 10.13%
- Indigestion: 7 people, 8.86%
- Multiple Allergies (allergy to multiple agents): 6 people, 7.59%
- Inflammation: 6 people, 7.59%
* Approximation only. Some reports may have incomplete information.
Do you take Augmentin and Patanol?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Augmentin and Patanol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Augmentin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Patanol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Augmentin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Patanol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium and olopatadine hydrochloride (the active ingredients of Augmentin and Patanol, respectively), and Augmentin and Patanol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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