Augmentin and Tresiba drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Tresiba (insulin degludec). Common drug interactions include anal abscess among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Tresiba. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Tresiba?

Tresiba has active ingredients of insulin degludec. It is often used in type 1 diabetes. eHealthMe is studying from 20,677 Tresiba users. Check the latest studies of Tresiba.

On Jul, 19, 2026

51 people who take Augmentin and Tresiba together, and have interactions are studied.

Augmentin and Tresiba drug interactions.

What are the common drug interactions of Augmentin and Tresiba, by gender? *:

female:

Anal abscess
Arthralgia (joint pain)
Asthenia (weakness)
Blood glucose decreased
Cellulitis (infection under the skin)
Chest pain
Constipation
Decreased appetite
Dry throat
Fall

male:

Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypotension (abnormally low blood pressure)
Lethargy (tiredness)
Pneumonia pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs)
Pyelonephritis (inflammation of kidney caused by bacteria)
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

What are the common drug interactions of Augmentin and Tresiba, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Blood glucose decreased
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Urticaria (rash of round, red welts on the skin that itch intensely)

30-39:

Anal abscess
Cellulitis (infection under the skin)
Chronic kidney disease
Genital abscess (build up of pus in genital)
Groin abscess (pus in groin)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Nephrogenic anaemia (anaemia due to kidney disease)
Nerve injury
Pain

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Abdominal discomfort
Blood glucose increased
Decreased appetite
Diarrhoea
Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Haematuria (presence of blood in urine)
Hypoglycaemia (deficiency of glucose in the bloodstream)

50-59:

Renal tubular necrosis (death of kidney tubules)
Subcutaneous abscess
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Community acquired infection (infection from community rather than hospital)
Dehydration (dryness resulting from the removal of water)
Hypotension (abnormally low blood pressure)
Pneumonia pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs)
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Anaemia (lack of blood)
Bacterial sepsis
Cough
Death
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Haemoglobin decreased
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Ill-defined disorder

What are the existing conditions these people have? *

Diabetes: 8 people, 15.69%
Pain: 7 people, 13.73%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 13.73%
Type 2 Diabetes: 6 people, 11.76%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 11.76%
Nausea (feeling of having an urge to vomit): 6 people, 11.76%
High Blood Pressure: 6 people, 11.76%
Stress And Anxiety: 5 people, 9.80%
Constipation: 5 people, 9.80%
Cardiac Disorder: 4 people, 7.84%

* Approximation only. Some reports may have incomplete information.

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