Augmentin and Urocit-k drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Urocit-k (potassium citrate). Common drug interactions include adrenal insufficiency among females and haemorrhage intracranial among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Urocit-k. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Urocit-k?

Urocit-k has active ingredients of potassium citrate. It is often used in kidney stones. eHealthMe is studying from 708 Urocit-k users. Check the latest studies of Urocit-k.



On Jul, 26, 2026

11 people who take Augmentin and Urocit-k together, and have interactions are studied.

Augmentin and Urocit-k drug interactions.

What are the common drug interactions of Augmentin and Urocit-K, by gender? *:

female:

  1. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  2. Metastases to bone marrow (cancer spreads to bone marrow)
  3. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Phlebitis (inflammation of the walls of a vein)
  6. Pulmonary mass
  7. Pyrexia (fever)
  8. Speech disorder
  9. Anaemia of malignant disease
  10. Arteriosclerosis (thickening and hardening of arteries)

male:

  1. Haemorrhage intracranial (bleeding within the skull)
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Lymphocyte count decreased
  4. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Platelet count decreased
  7. Pruritus (severe itching of the skin)
  8. White blood cell count decreased

What are the common drug interactions of Augmentin and Urocit-K, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Diarrhoea
  4. Drug intolerance (drug sensitivity)
  5. Duodenal polyp (duodenal epithelial tumours)
  6. Dysplasia (enlargement of an organ or tissue)
  7. Dystrophic calcification (calcification occurring in degenerated or necrotic tissue)
  8. Erythema (redness of the skin)
  9. Exposed bone in jaw
  10. Febrile neutropenia (fever with reduced white blood cells)

50-59:

  1. Arteriosclerosis (thickening and hardening of arteries)
  2. Arthralgia (joint pain)
  3. Asthenia (weakness)
  4. Back pain
  5. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  6. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  7. Bullous lung disease
  8. Cardiomegaly (increased size of heart than normal)
  9. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  10. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)

60+:

  1. Haemorrhage intracranial (bleeding within the skull)
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Lymphocyte count decreased
  4. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Platelet count decreased
  7. White blood cell count decreased

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 4 people, 36.36%
  2. Bone Loss: 4 people, 36.36%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 27.27%
  4. Lymphoma (cancer that begins in immune system cells): 3 people, 27.27%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 27.27%
  6. Quit Smoking: 1 person, 9.09%
  7. Prostatitis (inflammation of the prostate gland): 1 person, 9.09%
  8. Metastases To Bone (cancer spreads to bone): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Augmentin and Urocit-k:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Urocit-k:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Augmentin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Urocit-k and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium and potassium citrate (the active ingredients of Augmentin and Urocit-k, respectively), and Augmentin and Urocit-k (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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