Avalide and Magnesium oxide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avalide (hydrochlorothiazide; irbesartan) and Magnesium oxide (magnesium). Common drug interactions include rectal haemorrhage among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Avalide and Magnesium oxide. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Magnesium oxide?

Magnesium oxide has active ingredients of magnesium. It is often used in migraine. eHealthMe is studying from 19,022 Magnesium oxide users. Check the latest studies of Magnesium oxide.

On Jul, 16, 2026

36 people who take Avalide and Magnesium oxide together, and have interactions are studied.

Avalide and Magnesium oxide drug interactions.

What are the common drug interactions of Avalide and Magnesium Oxide, by gender? *:

female:

Rectal haemorrhage (bleeding from anus)
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Decreased appetite
Deformity (disfigurement)
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dysaesthesia (abnormal sensation)
Dyspnoea (difficult or laboured respiration)

male:

Fall
Back disorder
Anaemia (lack of blood)
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic valve incompetence
Arthralgia (joint pain)
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Breast cancer
Breast discharge
Breast hyperplasia (accumulation of abnormal cells in a breast duct)

What are the common drug interactions of Avalide and Magnesium Oxide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Anaemia (lack of blood)
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic valve incompetence
Arthralgia (joint pain)
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Breast cancer
Breast discharge
Breast hyperplasia (accumulation of abnormal cells in a breast duct)
Breast mass

40-49:

General physical health deterioration (weak health status)
Injury
Joint swelling
Lower extremity mass (mass in lower legs)
Mobility decreased (ability to move is reduced)
Muscle spasms (muscle contraction)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Pain in extremity

50-59:

Arthralgia (joint pain)
Decreased appetite
Deformity (disfigurement)
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dysaesthesia (abnormal sensation)
Gastric ulcer (stomach ulcer)
Herpes zoster
Infection
Insomnia (sleeplessness)

60+:

Rectal haemorrhage (bleeding from anus)
Dyspnoea (difficult or laboured respiration)
Muscle tightness
Renal impairment (severely reduced kidney function)
Staphylococcal infection (an infection with staphylococcus bacteria)
Anaemia (lack of blood)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Chest pain
Fluid retention (an abnormal accumulation of fluid in the blood)

What are the existing conditions these people have? *

Ovarian Cancer (cancer of ovary): 7 people, 19.44%
Multiple Myeloma (cancer of the plasma cells): 7 people, 19.44%
Diabetes: 4 people, 11.11%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 4 people, 11.11%
Hiv Infection: 3 people, 8.33%
Gastric Ulcer (stomach ulcer): 2 people, 5.56%
Dyspnea (difficult or laboured breathing): 2 people, 5.56%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 2 people, 5.56%
Fever: 2 people, 5.56%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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