Avalide and Ranitidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avalide (hydrochlorothiazide; irbesartan) and Ranitidine (ranitidine). Common drug interactions include renal failure among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Avalide and Ranitidine. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

On Jul, 06, 2026

73 people who take Avalide and Ranitidine together, and have interactions are studied.

Avalide and Ranitidine drug interactions.

What are the common drug interactions of Avalide and Ranitidine, by gender? *:

female:

Renal failure (kidney dysfunction)
Hypersensitivity
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Cardiac failure congestive
Gait disturbance
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Neck pain

male:

Chronic kidney disease
Fall
Deformity (disfigurement)
Depression
Diarrhoea
Erectile dysfunction
Nerve injury
Scar
Skin exfoliation (removal of the oldest dead skin cells)
Abdominal discomfort

What are the common drug interactions of Avalide and Ranitidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Infection
Drug ineffective
Pain
Stress
Weight decreased
Tendon operation
Headache (pain in head)
Hypersensitivity

30-39:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

40-49:

Depression
Fall
Activated partial thromboplastin time prolonged
Albumin globulin ratio decreased
Albumin urine present
Anaemia (lack of blood)
Anal haemorrhage
Anion gap decreased
Balance disorder
Blood creatinine increased

50-59:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Upper respiratory tract infection
Vascular calcification (deposits of calcium in the blood vessels)
Vomiting
Weight increased
Abdominal discomfort
Actinomyces test positive
Anxiety
Aphasia (damage to the parts of the brain that control language)
Arteriosclerosis (thickening and hardening of arteries)

60+:

Pneumonia
Chronic kidney disease
Abdominal pain upper
Agitation (state of anxiety or nervous excitement)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aphagia (inability or refusal to swallow)
Arthralgia (joint pain)
Blood glucose increased

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 23.29%
Pain: 9 people, 12.33%
High Blood Cholesterol: 7 people, 9.59%
Diabetes: 7 people, 9.59%
Stress And Anxiety: 6 people, 8.22%
Depression: 6 people, 8.22%

* Approximation only. Some reports may have incomplete information.

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