Avalide and Restoril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avalide (hydrochlorothiazide; irbesartan) and Restoril (temazepam). Common drug interactions include nasal congestion among females and pain in extremity among males.

The phase IV clinical study analyzes what interactions people have when they take Avalide and Restoril. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Restoril?

Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.

On Jul, 14, 2026

24 people who take Avalide and Restoril together, and have interactions are studied.

What are the common drug interactions of Avalide and Restoril, by gender? *:

female:

Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Neck injury
Neck pain
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteopenia (a condition where bone mineral density is lower than normal)
Palpitations (feelings or sensations that your heart is pounding or racing)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Presyncope
Pruritus (severe itching of the skin)
Rash

male:

Pain in extremity
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Bradycardia (abnormally slow heart action)
Cardiac murmur (an heart sound in valve abnormality)
Chest pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Disease recurrence

What are the common drug interactions of Avalide and Restoril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Foot deformity (functional disability of foot)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypertriglyceridaemia (excess of triglycerides in the blood)
Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)
Myalgia (muscle pain)
Nephrolithiasis (calculi in the kidneys)
Neuropathy peripheral (surface nerve damage)

50-59:

Back injury
Fall
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Intervertebral disc protrusion (spinal disc protrusion)
Limb injury
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Neck injury
Pain in extremity
Pruritus (severe itching of the skin)
Rash

60+:

Chest pain
Diarrhoea
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blood triglycerides increased
Bradycardia (abnormally slow heart action)
Cardiac murmur (an heart sound in valve abnormality)
Disease recurrence

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 20.83%
Pain: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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