Avalide and Theophyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avalide (hydrochlorothiazide; irbesartan) and Theophyl (theophylline). Common drug interactions include neuropathy peripheral among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Avalide and Theophyl. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Theophyl?

Theophyl has active ingredients of theophylline. eHealthMe is studying from 19,174 Theophyl users. Check the latest studies of Theophyl.

On Aug, 06, 2026

12 people who take Avalide and Theophyl together, and have interactions are studied.

What are the common drug interactions of Avalide and Theophyl, by gender? *:

female:

Neuropathy peripheral (surface nerve damage)
Abdominal adhesions (inflammation of abdomen)
Anxiety
Emotional distress
Fall
Hypoaesthesia (reduced sense of touch or sensation)
Injury
Pain
Pain in extremity
Small intestinal obstruction (blockage in small intestine)

male:

Blood glucose increased
Device failure
Urinary retention (the inability to completely or partially empty the bladder)
Disease recurrence
Dysphagia (a condition in which swallowing is difficult or painful)
Injection site pain
Prostatic disorder
Weight decreased
Abnormal dreams
Anger

What are the common drug interactions of Avalide and Theophyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Asthma
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Diabetic nephropathy (diabetic kidney disease)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Hyperglycaemia (high blood sugar)
Malaise (a feeling of general discomfort or uneasiness)
Neuropathy peripheral (surface nerve damage)
Pancreatic pseudocyst (collection of tissue and fluids that forms on pancreas)
Pancreatitis (inflammation of pancreas)

40-49:

n/a

50-59:

Injection site pain
Prostatic disorder
Weight decreased
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Colon cancer
Constipation
Depression
Dizziness

60+:

Abdominal adhesions (inflammation of abdomen)
Fall
Small intestinal obstruction (blockage in small intestine)
Wrist fracture
Injection site extravasation (flow of (blood or lymph) from injection site)
Injection site pain

What are the existing conditions these people have? *

Depression: 5 people, 41.67%
Asthma: 4 people, 33.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 25.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 16.67%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 16.67%
Quit Smoking: 2 people, 16.67%
Pain: 2 people, 16.67%
Cardiac Disorder: 2 people, 16.67%
Menopause (end of monthly cycles in women): 2 people, 16.67%
Stress And Anxiety: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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