Avapro and Astelin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avapro (irbesartan) and Astelin (azelastine hydrochloride). Common drug interactions include somnolence among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Avapro and Astelin. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.

On Jul, 11, 2026

74 people who take Avapro and Astelin together, and have interactions are studied.

What are the common drug interactions of Avapro and Astelin, by gender? *:

female:

Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain upper
Body height decreased
Bone pain
Difficulty in walking
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Fall
Fatigue (feeling of tiredness)
Gastritis (inflammation of stomach)
Headache (pain in head)

male:

Back pain
Headache (pain in head)
Abdominal pain upper
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Asthenia (weakness)
Chest discomfort
Chills (felling of cold)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Fatigue (feeling of tiredness)
Hepatic enzyme increased

What are the common drug interactions of Avapro and Astelin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

50-59:

Chills (felling of cold)
Headache (pain in head)
Hepatic enzyme increased
Hepatitis (inflammation of the liver)
Hyperhidrosis (abnormally increased sweating)
Influenza
Multiple myeloma (cancer of the plasma cells)
Myalgia (muscle pain)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasal discomfort

60+:

Blood alkaline phosphatase increased
Pancreatitis (inflammation of pancreas)
Insomnia (sleeplessness)
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Mobility decreased (ability to move is reduced)
Myalgia (muscle pain)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

Asthma: 9 people, 12.16%
Osteoporosis (bones weak and more likely to break): 9 people, 12.16%
Quit Smoking: 8 people, 10.81%
Headache (pain in head): 8 people, 10.81%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 10.81%
Lung Disorder (lung disease): 6 people, 8.11%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 8.11%
Depression: 6 people, 8.11%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 8.11%
Insomnia (sleeplessness): 6 people, 8.11%

* Approximation only. Some reports may have incomplete information.

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