Avapro and Exjade drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avapro (irbesartan) and Exjade (deferasirox). Common drug interactions include pain among females and vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Avapro and Exjade. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

What is Exjade?

Exjade has active ingredients of deferasirox. It is often used in iron overload. eHealthMe is studying from 29,456 Exjade users. Check the latest studies of Exjade.

On Jul, 10, 2026

35 people who take Avapro and Exjade together, and have interactions are studied.

What are the common drug interactions of Avapro and Exjade, by gender? *:

female:

Pain
Renal disorder (kidney disease)
White blood cell count decreased
Dizziness
Arthralgia (joint pain)
Blood urea increased
Dry skin
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)

male:

Vomiting
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Skin lesion
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Swelling face
Death
Neutropenia (an abnormally low number of neutrophils)
Haematocrit decreased
Haemoglobin decreased
Hepatomegaly (abnormal enlargement of the liver)

What are the common drug interactions of Avapro and Exjade, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood creatinine increased
Blood urea increased
Proteinuria (presence of protein in the urine)
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)

40-49:

n/a

50-59:

Blood alkaline phosphatase increased
Blood bilirubin increased
Blood bilirubin unconjugated increased
Blood chloride decreased
Blood creatinine decreased
Blood disorder
Blood lactate dehydrogenase increased
Blood potassium decreased
Blood sodium decreased
C-reactive protein increased

60+:

Vomiting
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Scab (a hard coating on the skin formed during the wound healing)
Skin exfoliation (removal of the oldest dead skin cells)
Skin lesion
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Swelling face
Blood glucose increased

What are the existing conditions these people have? *

Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 9 people, 25.71%
High Blood Cholesterol: 6 people, 17.14%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 8.57%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 2 people, 5.71%
Muscle Aches (muscle pain): 2 people, 5.71%
Haemosiderosis (general increase in tissue iron stores without associated tissue damage): 2 people, 5.71%
Diabetes: 2 people, 5.71%
Constipation: 2 people, 5.71%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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