Avapro and Inderal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avapro (irbesartan) and Inderal (propranolol hydrochloride). Common drug interactions include swelling face among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Avapro and Inderal. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

What is Inderal?

Inderal has active ingredients of propranolol hydrochloride. It is often used in migraine. eHealthMe is studying from 16,771 Inderal users. Check the latest studies of Inderal.

On Jul, 12, 2026

86 people who take Avapro and Inderal together, and have interactions are studied.

What are the common drug interactions of Avapro and Inderal, by gender? *:

female:

Swelling face
Urticaria (rash of round, red welts on the skin that itch intensely)
Abasia (inability to walk)
Adverse drug reaction
Adverse event
Amylase increased
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Anxiety disorder
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy

male:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Injury
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Decreased appetite
Dysgeusia (disorder of the sense of taste)
Dysphagia (a condition in which swallowing is difficult or painful)
Weight decreased
Hoarseness (changing voice)
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Avapro and Inderal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dry skin
Face oedema (swelling of face)
Lip dry
Blindness transient (sudden loss of vision)
Depression
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
Insomnia (sleeplessness)
Menstruation irregular
Photopsia (presence of perceived flashes of light)

40-49:

Blood cholesterol increased
Blood triglycerides increased
Blood glucose decreased
Cardiac disorder
Chest pain
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperlipidaemia (presence of excess lipids in the blood)
Mitral valve prolapse (heart's mitral valve doesn't work well)

50-59:

Throat tightness
Upper respiratory tract congestion
Chest pain
Diarrhoea
Vomiting
Agitation (state of anxiety or nervous excitement)
Constipation
Drug effect decreased
Oedema peripheral (superficial swelling)
Renal failure (kidney dysfunction)

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cardiac failure congestive
Anaemia (lack of blood)
Blood creatinine increased
Blood urea increased
Colonic polyp (extra part of colon tissue grow in intestine)
Drug dependence
Haemoglobin increased
Hypoaesthesia (reduced sense of touch or sensation)
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Depression: 8 people, 9.30%
Nuclear Magnetic Resonance Imaging Brain: 7 people, 8.14%
Immunodeficiency Common Variable: 7 people, 8.14%
Renal Artery Stenosis (narrowing of renal artery): 6 people, 6.98%
Nuclear Magnetic Resonance Imaging Abdominal: 6 people, 6.98%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 6 people, 6.98%
Chronic Renal Failure (kidney failure): 6 people, 6.98%
Cardiac Failure Congestive: 6 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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