Avapro and Pramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avapro (irbesartan) and Pramine (imipramine hydrochloride). Common drug interactions include hip deformity among females and dry skin among males.

The phase IV clinical study analyzes what interactions people have when they take Avapro and Pramine. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.

On Aug, 01, 2026

29 people who take Avapro and Pramine together, and have interactions are studied.

What are the common drug interactions of Avapro and Pramine, by gender? *:

female:

Hip deformity
Hyperhidrosis (abnormally increased sweating)
Hyperthyroidism (over activity of the thyroid gland)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Impaired driving ability
Headache (pain in head)
Weight increased
Cardiac murmur (an heart sound in valve abnormality)
Drug ineffective
Dyspnoea (difficult or laboured respiration)

male:

Dry skin
Joint range of motion decreased (disease of joint movement)
Oedema peripheral (superficial swelling)
Back pain
Depression
Hypoaesthesia (reduced sense of touch or sensation)
Joint swelling
Neck pain
Pain in extremity
Drug ineffective

What are the common drug interactions of Avapro and Pramine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Impaired driving ability
Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Influenza
Metastasis (spreadable cancer to other organ from origin)
Nausea (feeling of having an urge to vomit)
Nocturia (the need to get up in the night to urinate)
Obesity (having too much body fat)
Oropharyngeal pain
Pain
Pelvic venous thrombosis (blood clot occurring inside a blood vessel and thromboses (dvts) that form in the deep veins of the legs or in the pelvic veins)

50-59:

n/a

60+:

Oedema peripheral (superficial swelling)
Dry skin
Skin induration (an abnormally hard spot or area on the skin)
Hypoaesthesia (reduced sense of touch or sensation)
Pain in extremity
Peripheral coldness
Joint swelling
Abnormal dreams
Cardiac murmur (an heart sound in valve abnormality)
Cerebral artery occlusion (blockage of blood vessel of brain by fat or clot)

What are the existing conditions these people have? *

Sleep Apnea Syndrome: 5 people, 17.24%
Nuclear Magnetic Resonance Imaging Brain: 5 people, 17.24%
Headache (pain in head): 5 people, 17.24%
Brain Stem Syndrome: 5 people, 17.24%
Stress And Anxiety: 3 people, 10.34%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 10.34%
Type 2 Diabetes: 2 people, 6.90%
Migraine (headache): 2 people, 6.90%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 2 people, 6.90%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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