Avastin and Naprosyn drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Avastin (bevacizumab) and Naprosyn (naproxen). Common drug interactions include deformity among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Avastin and Naprosyn. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.
What is Avastin?
Avastin has active ingredients of bevacizumab. It is often used in high blood cholesterol. eHealthMe is studying from 76,365 Avastin users. Check the latest studies of Avastin.
What is Naprosyn?
Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.
45 people who take Avastin and Naprosyn together, and have interactions are studied.

What are the common drug interactions of Avastin and Naprosyn, by gender? *:
female:
- Deformity (disfigurement)
- Eye pain
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Hypophagia (reduced food intake)
- Impetigo (contagious skin infection)
- Injury
- Intervertebral disc disorder (spinal disc disorder)
- Joint stiffness
- Metastases to lung (cancer spreads to lung)
- Metastases to spine (cancer spreads to spine)
male:
- Death
- Fatigue (feeling of tiredness)
- Pulmonary embolism (blockage of the main artery of the lung)
- Disease progression
- Anaemia (lack of blood)
- Anxiety
- Depression
- Diarrhoea
- Emotional distress
- Fear
What are the common drug interactions of Avastin and Naprosyn, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Anal fistula
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Multi-organ failure (multisystem organ failure)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Oedema peripheral (superficial swelling)
- Pain in extremity
- Pulmonary embolism (blockage of the main artery of the lung)
- Septic shock (shock due to blood infection)
30-39:
- Diarrhoea
- Fall
- Fatigue (feeling of tiredness)
- Gait disturbance
- Muscular weakness (muscle weakness)
- Oedema peripheral (superficial swelling)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Sensory disturbance (sense disturbance)
- Urinary retention (the inability to completely or partially empty the bladder)
- Weight increased
40-49:
- Abdominal pain lower
- Cough
- Death
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Haemorrhage (bleeding)
- Headache (pain in head)
- Hypersensitivity
- Hypoaesthesia (reduced sense of touch or sensation)
- Ill-defined disorder
50-59:
- Bone pain
- Chest pain
- Cyst (a closed sac)
- Deformity (disfigurement)
- Discomfort
- Eye pain
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Hypophagia (reduced food intake)
- Impetigo (contagious skin infection)
- Intervertebral disc disorder (spinal disc disorder)
60+:
- Cardiomegaly (increased size of heart than normal)
- Neuropathy peripheral (surface nerve damage)
- Nephrolithiasis (calculi in the kidneys)
- Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
- Osteonecrosis of jaw (death of bone of jaw)
- Ovarian cyst (fluid filled sac of the ovary)
- Pain in extremity
- Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
- Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
- Quality of life decreased
What are the existing conditions these people have? *
- Breast Cancer: 10 people, 22.22%
- Multiple Myeloma (cancer of the plasma cells): 7 people, 15.56%
- Insomnia (sleeplessness): 7 people, 15.56%
- Breast Cancer Female: 5 people, 11.11%
- Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 8.89%
- Retinopathy Proliferative (a condition in which very small blood vessels grow from the surface of the retina and damages retina): 3 people, 6.67%
- Metastases To Bone (cancer spreads to bone): 3 people, 6.67%
- High Blood Pressure: 3 people, 6.67%
- Anaemia (lack of blood): 3 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Avastin and Naprosyn?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Avastin and Naprosyn:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Avastin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Naprosyn:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Avastin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Naprosyn and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on bevacizumab and naproxen (the active ingredients of Avastin and Naprosyn, respectively), and Avastin and Naprosyn (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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