Avastin and Vimpat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avastin (bevacizumab) and Vimpat (lacosamide). Common drug interactions include brain neoplasm malignant among females and hemiparesis among males.

The phase IV clinical study analyzes what interactions people have when they take Avastin and Vimpat. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Avastin?

Avastin has active ingredients of bevacizumab. It is often used in high blood cholesterol. eHealthMe is studying from 76,365 Avastin users. Check the latest studies of Avastin.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

On Jul, 17, 2026

89 people who take Avastin and Vimpat together, and have interactions are studied.

What are the common drug interactions of Avastin and Vimpat, by gender? *:

female:

Brain neoplasm malignant (brain cancer tumour)
Chapped lips (cracking, fissuring, and peeling of the skin f lip)
Cholecystitis acute (rapid infection of gallbladder)
Cystitis (inflammation of the wall of the bladder)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dizziness
Drug effect decreased
Drug ineffective
Dry skin

male:

Hemiparesis (weakness on one side of the body)
Muscular weakness (muscle weakness)
Oxygen saturation decreased
Weight decreased
Back pain
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Bacteraemia (presence of bacteria in the blood)
Pulmonary embolism (blockage of the main artery of the lung)
Asthenia (weakness)
Abscess limb (limb infection)

What are the common drug interactions of Avastin and Vimpat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Muscular weakness (muscle weakness)
Arthralgia (joint pain)
Balance disorder
Blood pressure increased
Blood pressure systolic increased
Contusion (a type of hematoma of tissue in which capillaries)
Fall
Foot fracture
Gingival bleeding (bleeding gums)
Hemiparesis (weakness on one side of the body)

30-39:

Grip strength decreased
Hand deformity
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Joint dislocation (a joint position is changed from normal position)
Lacrimation increased
Neoplasm progression (growth of tumour)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Paralysis

40-49:

Focal segmental glomerulosclerosis (scar tissue that forms in parts of the kidney called glomeruli)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Back pain
Hepatocellular injury (liver injury)
Rash pruritic (redness with itching)
General physical health deterioration (weak health status)
Glioma (a type of tumour that starts in the brain or spine)
Neoplasm progression (growth of tumour)

50-59:

Fingerprint loss
Peripheral swelling
Blindness
Eye pruritus (eye itching)
General physical health deterioration (weak health status)
Glossodynia (a burning or painful sensation in the tongue)
Hepatitis acute
Lip ulceration (ulcer of lip)
Mouth haemorrhage (bleeding from mouth)
Nasopharyngitis (inflammation of the nasopharynx)

60+:

Urinary tract infection
Abscess limb (limb infection)
Haemorrhage intracranial (bleeding within the skull)
Lung infection
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
Pneumonia
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Pyrexia (fever)
Red blood cell count decreased

What are the existing conditions these people have? *

Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 19 people, 21.35%
Brain Neoplasm Malignant (brain cancer tumour): 19 people, 21.35%
Lung Neoplasm Malignant (cancer tumour of lung): 11 people, 12.36%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 10 people, 11.24%
Central Nervous System Lesion (an abnormality in tissue of brain or spinal cord): 10 people, 11.24%
Anaplastic Astrocytoma (tumour of the glial (supportive) tissue of the brain): 7 people, 7.87%

* Approximation only. Some reports may have incomplete information.

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