Avelox and Isosorbide dinitrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avelox (moxifloxacin hydrochloride) and Isosorbide dinitrate (isosorbide dinitrate). Common drug interactions include nausea among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Avelox and Isosorbide dinitrate. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Avelox?

Avelox has active ingredients of moxifloxacin hydrochloride. It is often used in sinusitis. eHealthMe is studying from 28,651 Avelox users. Check the latest studies of Avelox.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

24 people who take Avelox and Isosorbide dinitrate together, and have interactions are studied.

Avelox and Isosorbide dinitrate drug interactions.

What are the common drug interactions of Avelox and Isosorbide Dinitrate, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Oropharyngeal pain
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Electrocardiogram qt prolonged
Hypokalaemia (low potassium)
Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
Abdominal mass (localized enlargement or swelling in the human abdomen)

male:

Cardiac failure congestive
Dyspnoea (difficult or laboured respiration)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dizziness
Emotional distress
Haematuria (presence of blood in urine)
Injury
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Avelox and Isosorbide Dinitrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cerebral atrophy (decrement in size of brain)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cold sweat
Confusional state
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetes mellitus inadequate control
Diabetic nephropathy (diabetic kidney disease)
Diarrhoea

60+:

Cardiac failure congestive
Dyspnoea (difficult or laboured respiration)
Hypokalaemia (low potassium)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Pain in extremity
Pulmonary oedema (fluid accumulation in the lungs)
Wheezing (a high-pitched whistling sound made while you breath)
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

What are the existing conditions these people have? *

High Blood Pressure: 3 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.50%
Chest Pain: 3 people, 12.50%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.33%
Pain: 2 people, 8.33%
Folate Deficiency (lack of folic acid): 2 people, 8.33%
Cardiac Failure Congestive: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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