Avonex and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avonex (interferon beta 1a) and Cyclophosphamide (cyclophosphamide). Common drug interactions include craniocerebral injury among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Avonex and Cyclophosphamide. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Avonex?

Avonex has active ingredients of interferon beta 1a. It is often used in multiple sclerosis. eHealthMe is studying from 198,544 Avonex users. Check the latest studies of Avonex.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

On Jul, 14, 2026

43 people who take Avonex and Cyclophosphamide together, and have interactions are studied.

Avonex and Cyclophosphamide drug interactions.

What are the common drug interactions of Avonex and Cyclophosphamide, by gender? *:

female:

Craniocerebral injury (injury to cranium and brain)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Epistaxis (bleed from the nose)
Hepatic steatosis (fatty liver disease)
Hip fracture
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Hysterectomy
Intestinal obstruction
Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
Post procedural haematoma (post procedural clotting of blood)

male:

Pneumonia
Back pain
Syncope (loss of consciousness with an inability to maintain postural tone)
Blindness
Malignant melanoma (skin cancer rises from melancytes)
Neoplasm malignant (cancer tumour)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Optic atrophy (the loss of a proportion of optic disc nerve fibres)
Influenza like illness
Abdominal pain upper

What are the common drug interactions of Avonex and Cyclophosphamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Hiv infection
Influenza like illness
Syncope (loss of consciousness with an inability to maintain postural tone)
Completed suicide (act of taking one's own life)
Suicidal ideation
Suicide attempt

20-29:

Asthenia (weakness)
Balance disorder
Blood follicle stimulating hormone increased
Blood luteinising hormone increased
Drug ineffective
Fall
Fatigue (feeling of tiredness)
Influenza like illness
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Muscular weakness (muscle weakness)

30-39:

Fatigue (feeling of tiredness)
Asthenia (weakness)
Balance disorder
Fall
Influenza like illness
Injection site bruising
Injection site discolouration
Tremor (trembling or shaking movements in one or more parts of your body)
Weight increased
White blood cell count decreased

40-49:

Constipation
Depressed level of consciousness
Drug hypersensitivity
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Febrile neutropenia (fever with reduced white blood cells)
Haemangioma of liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Malignant fibrous histiocytoma (a cancer tumour of uncertain origin that arises both in soft tissue and bone)
Nasopharyngitis (inflammation of the nasopharynx)

50-59:

Pneumonia
Myelosuppression (a decrease in the production of blood cells)
Back pain
Fatigue (feeling of tiredness)
Dysstasia (difficulty in standing)
Vomiting
Diarrhoea
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Breast cancer female

60+:

Breast cancer
Axillary vein thrombosis (formation of a blood clot in axillary vein)
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Back pain
Chills (felling of cold)
Coma (state of unconsciousness lasting more than six hours)
Depressed mood
Dyspnoea (difficult or laboured respiration)
Faecal occult blood (blood clot in stool)

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 11.63%

* Approximation only. Some reports may have incomplete information.

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