Avonex and Mestinon drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Avonex (interferon beta 1a) and Mestinon (pyridostigmine bromide). Common drug interactions include joint stiffness among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Avonex and Mestinon. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Avonex?
Avonex has active ingredients of interferon beta 1a. It is often used in multiple sclerosis. eHealthMe is studying from 198,544 Avonex users. Check the latest studies of Avonex.
What is Mestinon?
Mestinon has active ingredients of pyridostigmine bromide. It is often used in myasthenia gravis. eHealthMe is studying from 5,948 Mestinon users. Check the latest studies of Mestinon.
21 people who take Avonex and Mestinon together, and have interactions are studied.

What are the common drug interactions of Avonex and Mestinon, by gender? *:
female:
- Joint stiffness
- Influenza like illness
- Hip arthroplasty
- Pain
- Dyspnoea (difficult or laboured respiration)
- Ageusia (loss of taste functions of the tongue)
- Asthenia (weakness)
- Blood glucose increased
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cartilage injury
male:
- Drug ineffective
- Feeling cold
- Hyperhidrosis (abnormally increased sweating)
- Insomnia (sleeplessness)
- Pneumonia
- Renal failure (kidney dysfunction)
- Septic shock (shock due to blood infection)
- Swelling
- Tremor (trembling or shaking movements in one or more parts of your body)
What are the common drug interactions of Avonex and Mestinon, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Blood glucose increased
- Dyspnoea (difficult or laboured respiration)
- Influenza like illness
- Asthenia (weakness)
- Cardiac failure
- Cold sweat
- Dizziness
- Drug ineffective
- Feeling cold
- Hyperhidrosis (abnormally increased sweating)
40-49:
- Lipoma (a growth of fatty tissue that slowly develops just under your skin)
- Monocytosis (an increase in the number of monocytes circulating in the blood)
- Thrombocytopenia (decrease of platelets in blood)
50-59:
- Groin pain
- Joint stiffness
- Hip arthroplasty
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Chills (felling of cold)
- Influenza like illness
- Pain
- Cardiac pacemaker removal
- Hyperaesthesia
- Hyperreflexia (overactive or over responsive reflexes)
60+:
- Fatigue (feeling of tiredness)
- Asthenia (weakness)
- Bladder disorder
- Constipation
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Pain
- Procedural pain
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Urinary retention (the inability to completely or partially empty the bladder)
What are the existing conditions these people have? *
- Muscle Spasms (muscle contraction): 2 people, 9.52%
- Multiple Allergies (allergy to multiple agents): 2 people, 9.52%
- Influenza Like Illness: 2 people, 9.52%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 9.52%
- High Blood Cholesterol: 2 people, 9.52%
- Fatigue (feeling of tiredness): 2 people, 9.52%
- Eye Pain: 2 people, 9.52%
- Dyskinesia (abnormality or impairment of voluntary movement): 2 people, 9.52%
- Bone Disorder: 2 people, 9.52%
* Approximation only. Some reports may have incomplete information.
Do you take Avonex and Mestinon?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Avonex and Mestinon:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Avonex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Mestinon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Avonex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mestinon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on interferon beta 1a and pyridostigmine bromide (the active ingredients of Avonex and Mestinon, respectively), and Avonex and Mestinon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Drug interactions of Avelox and Loraz - a second ago
- Could Vesicare cause Movement - Uncontrolled Or Slow? - 7 seconds ago
- Could Avalide cause Insomnia? - 20 seconds ago
- Could Avelox cause Plasmacytosis? - 24 seconds ago
- Could Q10 cause Muscle Tightness? - 25 seconds ago
- Could Verapamil Hcl cause Presyncope? - 37 seconds ago
- Drug interactions of Promethazine and Gentamicin - 42 seconds ago
- Drug interactions of Magnevist and Lantus - 46 seconds ago
- Could Marijuana cause Psoriatic Arthropathy Aggravated? - a minute ago
- Could Pyridostigmine Bromide cause Dyspnea Exacerbated? - a minute ago