Avonex and Methylphenidate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avonex (interferon beta 1a) and Methylphenidate (methylphenidate). Common drug interactions include asthenia among females and bradycardia among males.

The phase IV clinical study analyzes what interactions people have when they take Avonex and Methylphenidate. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Avonex?

Avonex has active ingredients of interferon beta 1a. It is often used in multiple sclerosis. eHealthMe is studying from 198,544 Avonex users. Check the latest studies of Avonex.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,216 Methylphenidate users. Check the latest studies of Methylphenidate.

On Jul, 10, 2026

13 people who take Avonex and Methylphenidate together, and have interactions are studied.

Avonex and Methylphenidate drug interactions.

What are the common drug interactions of Avonex and Methylphenidate, by gender? *:

female:

Asthenia (weakness)
Decreased immune responsiveness
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Peripheral swelling
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting

male:

Bradycardia (abnormally slow heart action)
Device related infection
Fatigue (feeling of tiredness)
Mobility decreased (ability to move is reduced)
Visual impairment

What are the common drug interactions of Avonex and Methylphenidate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Atonic seizures (minor type of seizure)
Fall
Head injury
Memory impairment
Hospitalisation

60+:

Decreased immune responsiveness
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
White blood cell count decreased
White blood cell count increased
Bradycardia (abnormally slow heart action)
Device related infection
Fatigue (feeling of tiredness)
Mobility decreased (ability to move is reduced)
Visual impairment
Depression

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 23.08%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 23.08%
Gait Disturbance: 2 people, 15.38%
Pain: 1 person, 7.69%
Muscle Spasms (muscle contraction): 1 person, 7.69%
Fatigue (feeling of tiredness): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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