Avonex and Plendil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avonex (interferon beta 1a) and Plendil (felodipine). Common drug interactions include influenza like illness among females.

The phase IV clinical study analyzes what interactions people have when they take Avonex and Plendil. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Avonex?

Avonex has active ingredients of interferon beta 1a. It is often used in multiple sclerosis. eHealthMe is studying from 198,544 Avonex users. Check the latest studies of Avonex.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

14 people who take Avonex and Plendil together, and have interactions are studied.

What are the common drug interactions of Avonex and Plendil, by gender? *:

female:

Influenza like illness
Migraine (headache)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Dyspnoea (difficult or laboured respiration)
Eye oedema (swelling or thickening of the macula, the area of the retina responsible for central vision)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Pain in extremity
Pneumonia
Urinary retention (the inability to completely or partially empty the bladder)

male:

n/a

What are the common drug interactions of Avonex and Plendil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain upper
Dyspnoea (difficult or laboured respiration)
Eye oedema (swelling or thickening of the macula, the area of the retina responsible for central vision)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Influenza like illness
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Migraine (headache)

40-49:

n/a

50-59:

Anaemia (lack of blood)
Influenza like illness
Diarrhoea
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematocrit decreased
Kidney fibrosis (excess fibrous connective tissue in kidney)
Meningitis chemical (chemical exposure causes inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Migraine (headache)
Nephrosclerosis (hardening of the kidney due to renovascular disease)
Pain in extremity

60+:

n/a

* Approximation only. Some reports may have incomplete information.

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