Axid and Requip drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Axid (nizatidine) and Requip (ropinirole hydrochloride). Common drug interactions include anxiety among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Axid and Requip. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Axid?

Axid has active ingredients of nizatidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 2,980 Axid users. Check the latest studies of Axid.

What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

23 people who take Axid and Requip together, and have interactions are studied.

What are the common drug interactions of Axid and Requip, by gender? *:

female:

Anxiety
Fatigue (feeling of tiredness)
Pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Decreased appetite
Lymphadenopathy (disease or enlargement of lymph nodes)
Lymphoma (cancer that begins in immune system cells)
Rhinorrhoea (watery mucus discharge from the nose)
Vomiting

male:

Weight decreased
Arthralgia (joint pain)
Abdominal pain
Abdominal wound dehiscence (abdominal wound ruptures)
Acute leukaemia (blood cancer)
Altered state of consciousness (altered state of mind)
Anaemia (lack of blood)
Anxiety
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Axid and Requip, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Anxiety
Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

50-59:

Foot fracture
Gastric cancer recurrent (repeat stomach cancer)
Gastric ulcer (stomach ulcer)
Gingival pain (gum pain)
Haemophilus bacteraemia (bacterial infection by haemophilus influenzae)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Helicobacter test positive
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)

60+:

Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Acquired macroglossia (large tongue)
Acute respiratory failure
Alopecia (absence of hair from areas of the body)
Anticonvulsant drug level above therapeutic
Anxiety
Aortic valve sclerosis (narrowing of the aortic valve)
Arrhythmia (irregular heartbeat)
Atrial hypertrophy (a condition where the left atrium or right atrium of the heart is larger than would be expected)

What are the existing conditions these people have? *

Quit Smoking: 6 people, 26.09%
Depression: 5 people, 21.74%
Pain: 5 people, 21.74%
Thyroid Diseases: 4 people, 17.39%
Insomnia (sleeplessness): 4 people, 17.39%
Asthma: 4 people, 17.39%
Headache (pain in head): 4 people, 17.39%
Stress And Anxiety: 4 people, 17.39%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 17.39%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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