Axid and Vasotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Axid (nizatidine) and Vasotec (enalapril maleate). Common drug interactions include muscle spasms among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Axid and Vasotec. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Axid?

Axid has active ingredients of nizatidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 2,980 Axid users. Check the latest studies of Axid.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

On Jul, 03, 2026

70 people who take Axid and Vasotec together, and have interactions are studied.

What are the common drug interactions of Axid and Vasotec, by gender? *:

female:

Muscle spasms (muscle contraction)
Vomiting
Abdominal pain
Chest pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug effect decreased
Hepatomegaly (abnormal enlargement of the liver)
Osteonecrosis of jaw (death of bone of jaw)
Anxiety
Arrhythmia (irregular heartbeat)

male:

Dyspnoea (difficult or laboured respiration)
Aspartate aminotransferase increased
Difficulty in walking
Fatigue (feeling of tiredness)
Gamma-glutamyltransferase increased
Lethargy (tiredness)
Listless (lack of interest, energy, or spirit)
Myalgia (muscle pain)
Prostatic specific antigen increased
Sedation

What are the common drug interactions of Axid and Vasotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Headache (pain in head)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arrhythmia (irregular heartbeat)
Arthralgia (joint pain)
Asthenia (weakness)
Asthma
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrioventricular block complete (heart block complete)
Back pain
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

40-49:

Headache (pain in head)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cough
Depression
Diarrhoea
Fungal rash
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatomegaly (abnormal enlargement of the liver)
Liver fatty (fat deposition of liver)
Abdominal adhesions (inflammation of abdomen)

50-59:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depressed level of consciousness
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Electrocardiogram qrs complex prolonged
Femur fracture
Haematoma (collection of blood outside the blood vessels)
Hepatic failure (liver failure)
Implant site reaction
International normalised ratio increased
Pruritus (severe itching of the skin)

60+:

Nausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)
Anaemia (lack of blood)
Aspartate aminotransferase increased
Cardiac failure congestive
Drug effect decreased
Osteonecrosis of jaw (death of bone of jaw)
Pain
Renal failure (kidney dysfunction)
Sedation

* Approximation only. Some reports may have incomplete information.

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