Axiron and Lortab drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Axiron (testosterone) and Lortab (acetaminophen; hydrocodone bitartrate). Common drug interactions include coronary artery disease among males.

The phase IV clinical study analyzes what interactions people have when they take Axiron and Lortab. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Axiron?

Axiron has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 7,703 Axiron users. Check the latest studies of Axiron.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

On Jul, 18, 2026

20 people who take Axiron and Lortab together, and have interactions are studied.

What are the common drug interactions of Axiron and Lortab, by gender? *:

female:

n/a

male:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cardiac disorder
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiomegaly (increased size of heart than normal)
Cardiovascular disorder (heart diseases)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Diastolic dysfunction
Hepatocellular carcinoma (liver cancer)
Lung disorder (lung disease)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

What are the common drug interactions of Axiron and Lortab, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Depression
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Osteoporosis (bones weak and more likely to break)
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
Skin burning sensation
Spinal compression fracture (fracture due to spinal compression on bone)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)

30-39:

n/a

40-49:

Anaemia (lack of blood)
Cardiac disorder
Cerebrovascular disorder (disease of brain)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Hemiplegic migraine (migraine attacks occurring in two or more people in the same family who experience weakness on one side of body)
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Thrombosis (formation of a blood clot inside a blood vessel)
Vasculitis (inflammation of a blood vessel or blood vessels)

50-59:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiovascular disorder (heart diseases)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diastolic dysfunction
Hepatocellular carcinoma (liver cancer)
Lung disorder (lung disease)
Pulmonary embolism (blockage of the main artery of the lung)
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute myocardial infarction (acute heart attack)

60+:

Asthenia (weakness)
Cardiac disorder
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diarrhoea
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Suicidal ideation
Ventricular extrasystoles (premature cardiac contraction)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the existing conditions these people have? *

Blood Testosterone Decreased: 12 people, 60.00%
High Blood Pressure: 6 people, 30.00%
High Blood Cholesterol: 5 people, 25.00%
Back Pain: 5 people, 25.00%
Diabetes: 5 people, 25.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 25.00%
Muscle Spasms (muscle contraction): 3 people, 15.00%
Erection Problems: 3 people, 15.00%
Inflammation: 2 people, 10.00%
Renal Disorder (kidney disease): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Axiron and Lortab?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously