Aygestin and Humira drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aygestin (norethindrone acetate) and Humira (adalimumab). Common drug interactions include injection site haemorrhage among females.

The phase IV clinical study analyzes what interactions people have when they take Aygestin and Humira. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Aygestin?

Aygestin has active ingredients of norethindrone acetate. It is often used in endometriosis. eHealthMe is studying from 1,107 Aygestin users. Check the latest studies of Aygestin.

What is Humira?

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,396 Humira users. Check the latest studies of Humira.

On Jul, 08, 2026

14 people who take Aygestin and Humira together, and have interactions are studied.

What are the common drug interactions of Aygestin and Humira, by gender? *:

female:

Injection site haemorrhage (bleeding from injection site)
Injection site pain
Injection site rash
Seasonal allergy (allergic condition due to certain season)
Abdominal pain
Abdominal pain upper
Arthralgia (joint pain)
Asthenia (weakness)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac disorder

male:

n/a

What are the common drug interactions of Aygestin and Humira, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Injection site pain

20-29:

Injection site bruising
Injection site haemorrhage (bleeding from injection site)
Abdominal pain upper
Chills (felling of cold)
Dermatitis allergic (inflammation of the skin due allergic reaction)
Headache (pain in head)
Hidradenitis (chronic disease of a type of sweat gland)
Injection site erythema (redness at injection site)
Injection site pruritus (severe itching at injection site)
Injection site urticaria (rash of round, red welts on the skin at injection site)

30-39:

Urinary tract infection
Injection site haemorrhage (bleeding from injection site)
Injection site pain
Nasopharyngitis (inflammation of the nasopharynx)
Seasonal allergy (allergic condition due to certain season)
Abdominal pain
Arthralgia (joint pain)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac failure congestive

40-49:

Asthenia (weakness)
Cardiac disorder
Chest pain
Dizziness
Dyspnoea (difficult or laboured respiration)
Hepatic enzyme increased
Intentional self-injury
Nasopharyngitis (inflammation of the nasopharynx)
Procedural site reaction
Rash

50-59:

Asthma
Candidiasis (candidiasis or thrush is a fungal infection)
Sinusitis (inflammation of sinus)
Vaginal discharge
Cough
Headache (pain in head)
Injection site haematoma (localized swelling filled with blood at injection site)
Injection site pain
Injection site rash
Oropharyngeal pain

60+:

n/a

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 35.71%
Depression: 4 people, 28.57%
Migraine (headache): 4 people, 28.57%
High Blood Pressure: 3 people, 21.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 21.43%
Stress And Anxiety: 3 people, 21.43%
Asthma: 3 people, 21.43%
Pain: 3 people, 21.43%
Birth Control: 3 people, 21.43%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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